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Mouse anti Human B7.1 (extra-cellular domain)

Catalogue number: 0861

Product Type Monoclonal Antibody
Units100 µg
Species reactivity Human
Application Flow Cytometry

Cell Distribution: CD86 antibody is rapidly induced on the surface of and is expressed at high levels on dendritic cells. It is also found on malignant Hodgkin and Reed-Sternberg (H-RS) cells in HodgkinÕs disease. Function: CD86 is one of two ligands (the other CD80) for CTLA4 and CD28. CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation. Antigen presentation in the absence of sufficient costimulation involving CD86/CD80 can induce tolerance. CD80 appears to play a role distinct from CD80 in T helper cell differentiation.

Synonyms: CD86, mouse Anti Human B7.2 unconjugated


Immunogen: Recombinant expressed extra-cellular domain of human CD86.


Product Form: Unconjugated

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Purification Method: Protein A/G Chromatography

Purity: > 95 % by SDS PAGE

Concentration: See vial for concentration

Antibody can be used for flow cytometry and immunohistochemistry. Optimal concentration should be evaluated by serial dilutions.

Functional Analysis: Western Blotting, Flow cytometry, Immunohistochemistry.

Positive Control: Specificity: Recognizes the extra-cellular domain of human CD86 (also called B7-2). Does not bind the extracellular domain of CD80.

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: Products are stable for one year from purchase when stored properly

Ship Conditions: Ship at ambient temperature, freeze upon arrival

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

1. Chan, E.P.H., et al. 'Effects of titanium(IV) ions on human monocyte-derived dendritic cells.' Metallomics 2009, 1, 166-174.

Protein Reference(s)

Database Name: UniProt

Accession number: P42081

Safety Datasheet(s) for this product:
Sodium Azide

Mouse anti Human B7.1 (extra-cellular domain)



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Phone: 978-425-1370