Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

c-myc

  • Product Code: n110m
  • Size: 100 µg
  • Price (USD): $244

Cat #

n110m		 Quantity:      

Product Name

c- myc

Synonyms

cmyc; Myc proto-oncogene protein; transcription factor p64

Host/Source

Mouse

Clone

8

Isotype

IgG2a

Product Type

Monoclonal Antibody

Reactivity

Human, Mouse, Rat

Applications

Western Blot, Immunoprecipitation

Purification

Protein A/G Chromatography

Size

100 µg

Price (USD)

$244

Background

Human c-myc belongs to a family of 5 myc oncogenes. Amplification of c-myc has been found in several tpes of human tumors including breast and colon carcinomas. Induction of c-myc in cells grown in the appropriate growth factors or co-expression with survival genes, such as bcl-2 causes cell proliferation. In the abscence of these factors, c-myc expression causes cell death. c-myc gene gives rise to at least two nuclear phosphoproteins of 64kDa and 67kDa.

Immunogen

Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant full-length human c-Myc protein and mouse myeloma cells.

Formulation

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight

48.8

Database Links:

SwissProtP09416Rat
SwissProtP01108Mouse
SwissProtP01106Human

References

1) K. Alitala et. al. (1983) Proc. Natl. Acad. Sci., 80: 1707-1711

2)H. Person et.al. (1984) Science 225 687-693