Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

Phospho Sphingosine Kinase 1 (Ser225), Mouse

  • Product Code: X1877B
  • Size: 50 µg
  • Price (USD): $113

Cat #

X1877B		 Quantity:      

Data Sheet

Product Name

Phospho Sphingosine Kinase 1 (Ser225), Mouse

Product Type

Blocking Peptide

Applications

Antibody function blocking

Size

50 µg

Price (USD)

$113

Background

Sphingosine kinase 1 catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (spp)(sphingosine + ATP = sphingosine 1-phosphate + ADP), a lipid mediator with both intra- and extracellular functions. also acts on d-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as d,l-threo-dihydrosphingosine, n,n-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol. The long form of sphingosine kinase 1, an N-terminal extension, is responsible for FceRI-mediated calcium mobilization and may play a role in other ligand mediated signaling events.

Formulation

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Database Links:

SwissProtQ8CI15Mouse