Exalpha Biologicals, Inc.

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Exalpha Biologicals, Inc. is now a US distributor for Nordic-Mubio products

Nordic-MUbio develops and manufactures high quality antibody reagents for use in R&D. All our products are manufactured according to strict ISO 9001 quality guidelines, and our focus is on developing antibodies targetting Cell Adhesion, Nuclear and Cytoskeletal Proteins.

Nordic-MUbio is one of the leading antibody companies developing antibodies for zebrafish research – we currently have over 50 antibodies validated for immunofluorescence in zebrafish.

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Latest References

Akazawa, Y., et al. "Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis" PLoS ONE 8(12): e82322

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Homa, N.J., et al. "Epstein-Barr Virus Induces Global Changes in Cellular mRNA Isoform Usage That Are Important for the Maintenance of Latency" J. Virol., 2013, 87, 12291-12301

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Exalpha Biologicals, Inc.

PTPIA2 (693-979)

  • Product Code: X1774E
  • Size: 20 µg
  • Availability: In Stock In Stock
  • Price (USD): $361

Cat #

X1774E		 Quantity:      

Data Sheet

Product Name

PTPIA2 (693-979)

Synonyms

Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N; Islet cell antigen 512; ICA 512; Islet cell autoantigen 3; PTPRN

Host/Source

E.coli

Product Type

Active Enzyme

Reactivity

Human

Applications

Study of enzyme kinetics, regulation, and to dephosphorylate target substrates.

Size

20 µg

Price (USD)

$361

Background

Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2. Interacts with phosphorylated SNTB2, protecting it from protein cleavage by CAPN1. Dephosphorylation of SNTB2 upon insulin stimulation disrupts the interaction and results in its cleavage.

Immunogen

E. Coli

Formulation

Provided in 50 mM Tris-HCl, pH 8.0, 137 mM NaCl, 2.7 mM KCl, 3 mM DTT, 20 mM glutathione.

Customer Storage

Products should be stored at -80°C. Aliquot to avoid freeze/thaw cycles.

Database Links:

GenBank002846Human

References

1. T. Ort et al., EMBO J. 2001, 20: 4013-23

2. Z. Li et al., J Histochem Chytochem. 2000, 48:761-7