Exalpha Biologicals, Inc.

Product Highlight

FIX&PERM Cell Fixation and Permeabilization Kit

Flow cytometric analyses with monoclonal antibodies were so far mainly restricted to cell surface molecules. Intracellular structures such as cytoplasmic or nuclear enzymes, oncoproteins, cytokines, immunoglobulins etc. were largely excluded from such studies. Also excluded from flow cytometric studies were cytoplasmic localizations of well-established membrane molecules like CD3 and CD22, which, in their cytoplasmic form, are the most reliable lineage markers in undifferentiated leukemia. With the FIX&PERM® Kit flow cytometric analysis of intracellular antigens has become as easy as surface antigen studies. The only prerequisite is the availability of suitable antibody conjugates. Most of the available monoclonal antibody conjugates can be used with the FIX&PERM® Kit, some determinants are sensitive, however, to the fixation step involved. This and the optimal fixation time have to be tested for each reagent.

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Welcome, Peter Rutten

We are pleased to announce that Peter Rutten has now started in his role as Operations Director here at Exalpha Biologicals Inc. Peter has a Master’s of Science degree in Industrial and Organizational Psychology and this has lead him down a very business orientated career path. Peter is looking forward to working with the team at Exalpha. Peters primary focus is the customer experience and he will be working with the Laboratory team, the Quality Control team and the Order Processing team to ensure this focus is achieved. We all wish Peter well in his new role.

Exalpha Biologicals, Inc.

GPR3

  • Product Code: X1655P
  • Size: 100 µg
  • Availability: In Stock In Stock
  • Price (USD): $355

Cat #

X1655P		 Quantity:      

Data Sheet

Product Name

GPR3

Synonyms

Probable G Protein-Coupled Receptor GPR3

Host/Source

Rabbit

Isotype

IgG

Product Type

Antigen Immunoaffinity Purified Polyclonal

Reactivity

Human

Applications

Western Blot, Enzyme Immunoassay

Purification

Antigen Immunoaffiinity Purification

Size

100 µg

Price (USD)

$355

Background

Orphan receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Expressed predominantly in the central nervous system, and at low levels in the lung, kidney, testis, ovary and eye. Belongs to the G-protein coupled receptor 1 family.

Immunogen

Synthetic peptide derived from the extracellular N-terminal region of the GPR3 protein

Positive Control

Human brain

Formulation

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight

35 kDa

Database Links:

SwissProtP46089Human

References

1. Iismaa, T.P., et al. 'Isolation and chromosomal localization of a novel human G-protein-coupled receptor (GPR3) expressed predominantly in the central nervous system.' Genomics 1994, 24(2):391-394

2. Eggerickx, D., et al. 'Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase.' Biochem. J. 1995, 309:837-843