Exalpha Biologicals, Inc.

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Exalpha Biologicals, Inc. is now a US distributor for Nordic-Mubio products

Nordic-MUbio develops and manufactures high quality antibody reagents for use in R&D. All our products are manufactured according to strict ISO 9001 quality guidelines, and our focus is on developing antibodies targetting Cell Adhesion, Nuclear and Cytoskeletal Proteins.

Nordic-MUbio is one of the leading antibody companies developing antibodies for zebrafish research – we currently have over 50 antibodies validated for immunofluorescence in zebrafish.

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Latest References

Akazawa, Y., et al. "Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis" PLoS ONE 8(12): e82322

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Homa, N.J., et al. "Epstein-Barr Virus Induces Global Changes in Cellular mRNA Isoform Usage That Are Important for the Maintenance of Latency" J. Virol., 2013, 87, 12291-12301

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Exalpha Biologicals, Inc.

Lysophosphatidic Acid Receptor 1 CT (EDG-2)

  • Product Code: X1269B
  • Size: 50 µg
  • Availability: In Stock In Stock
  • Price (USD): $113

Cat #

X1269B		 Quantity:      

Data Sheet

Product Name

Lysophosphatidic Acid Receptor 1 CT (EDG-2)

Synonyms

Blocking peptide for use in Western blotting with Anti-EDG2 (LPA1) (CT) (Cat. No. C174P)

Host/Source

N/A

Isotype

N/A

Product Type

Blocking Peptide

Applications

Antibody function blocking

Size

50 µg

Price (USD)

$113

Background

Endothelial cell differentiation gene-2 (EDG2), or LPA1, receptor is a high affinity receptor for lysophosphatidic acid (LPA). EDG2 (LPA1), also known as lysophospholipid receptor A1, Vzg-1, mrec1.3 or GPCR26, like all other EDG receptors, couple multiple (3 or more) types of G proteins and transduce decreases in c[AMP]i through Gi and increases in [Ca2+]i by augmenting phospholipase C through Gq/11 and beta/gamma dimers and by induction of PI3 kinase, p125 FAK, phospholipase D by activating rho through G12/13. Human EDG2 (LPA1) is present in high levels on oligodendrocytes and certain human malignant T cell lines. EDG2 (LPA1) receptors (with EDG4) may play a role in protecting cardiomyocytes from apoptosis induced by hypoxia and andrenergic stimulation.

Formulation

Provided in solution at 1 mg/ml in phosphate buffered saline.

Customer Storage

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles