Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

Parc-Biotin

  • Product Code: X1247C
  • Size: 20 µg
  • Price (USD): $450

Cat #

X1247C		 Quantity:      

Product Name

Parc-Biotin

Synonyms

Pulmonary and Activation-Related Chemokine-1, AMAC-1, MIP-4, DC-CK1, Synthetic Protein, Biotin Conjugate

Product Type

Synthetic Protein

Applications

Activity Assay

Size

20 µg

Price (USD)

$450

Background

Pulmonary and activation-regulated chemokine (PARC)-1, which has also been identified as alternative macrophage activation-associated CC chemokine-1 (AMAC-1), Macrophage Inflammatory Protein-4 (MIP-4) and dendritic cell chemokine (DC-CK1), is a novel CC chemokine which shares 61% sequence homology with MIP-1?. PARC-1 cDNA encodes an 89 amino acid protein which contains a 20 amino acid signal peptide that is cleaved to generate the mature 69 amino acid protein lacking glycosylation sites. PARC-1 is highly expressed in lung and placenta but is not expressed in epidermal Langerhans cells.

Formulation

Lyophilized

Customer Storage

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

References

1. Guan, P. et al. Genomic organization and biological characterization of the novel human CC chemokine DC-CK-1/PARC/MIP-4/SCYA18. Genomics 1999, 56, 296-302 2. Reape, T.J., et al. Expression and cellular localization of the CC chemokines PARC and ELC in human atherosclerotic plaques. Am. J. Pathol. 1999, 154, 365-374 3. Hieshima, K., et al. A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein 1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes. J. Immunol. 1997, 159, 1140-1149