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VEGFR-1/FLT-1, human N-term.


Catalogue number: VEGR101

Clone7G96
IsotypeIgG1
Units100 µg
HostMouse
Application IHC
Immunohistochemistry
WB
Western Blotting
Background
Endothelial cells express three different receptors for vascular endothelial growth factors (VEGF). The induction of angiogenesis by VEGF-C and VEGF-A is mediated by VEGF-Receptors 2 and -3, while VEGF-B is bound by VEGF-Receptor-1 only. VEGF-D also acts trough VEGFR-3 in lymphangiogenesis and tumour metastasis. A naturally occuring soluble variant of VEGFR-1 was found in HUVE supernatants. It is generated by alternative splicing. Human VEGFR-1, no reactivity with VEGFR-2 and VEGFR-3 in Western Blot.

Positive Control
HUVE

Pre-Treatment
IHC pre-treatment not established, unmasking fluid G (DE007) or Unmasking fluid T (DE005) may be advantageous.

Immunogen
Recombinant N-terminal fragment of human VEGFR-1 (extracellular domain aa 27 to aa 687)

Purification Method
Protein G affinity purified antibody lyophilised without additional stabilizers

Working Concentration
(lyophilisate)

Concentration
100 µg

Secondary Reagents
We recommend the use of BIOLOGO's Universal Staining System DAB (Art. No. DA005) or AEC (Art. No. AE005).

Product
Protein G affinity purified antibody lyophilised without additional stabilizers

Applications
WB, IHC

Cross Reactivity
Human, other species not tested

Storage
-20°C

References
Vascular Growth Factors and Angiogenesis Editor: Lena Claesson-Welsh – 2012 (Springer)

Caution
These antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.

Safety Datasheet(s) for this product:

VEGFR-1/FLT-1, human N-term.

$791.00

SKU: VEGR101 Categories: ,

Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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