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Rabbit anti Rat BAG-5

Catalogue number: X1596P

Product Type Polyclonal Antibody
Units100 µg
Species reactivity Rat
Application Immunohistochemistry (Paraffin Sections)
Western Blot
Product Form

It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70Õs anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAG heterodimerization.

Synthetic peptide derived from the human BAG-5 protein.

Purification Method
Ammonium Sulfate Precipitation

See vial for concentration

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Functional Analysis
Western Blotting

Anibody can be used for Western blotting (5-10 µg/ml). Optimal concentration should be evaluated by serial dilutions.

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Ship Conditions
Ship at ambient temperature, freeze upon arrival

Product Stability
Products are stable for one year from purchase when stored properly

1. Takayama,S., et al. 'An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.' J. Biol. Chem. 1999, 274: 781-786

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

Safety Datasheet(s) for this product:

Sodium Azide

Rabbit anti Rat BAG-5