Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery

Product Highlight

Mouse anti-M13 phage coat protein g8p

Antibodies recognising M13 filamentous phage coat proteins are instrumental in the selection and detection of phages expressing specific antibody fragments or peptide sequences at their surface. The monoclonal antibodies manufactured and supplied by Exalpha react with either the pIII (g3p) or pVIII (g8p) proteins of M13 filamentous bacteriophage. All antibodies are available in a purified format. The antibodies are fully validated and are suitable for a wide range of techniques including:

  • ELISA
  • Flow Cytometry
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
For more information, click here for our M13 Bacteriophage information page.

News

Two more of our excellent products have been published by PubMed:

Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis
Borazanci, E., et al., J. Gastrointest. Oncol., 8, 164-172 (2017)
Using Exalpha SPARC Antibody (Cat. No. X1867P)

Molecular mechanism underlying the pharmacological interactions of the protein kinase C-β inhibitor enzastaurin and erlotinib in non-small cell lung cancer cells
Steen, N.V., et al., Am. J. Cancer Res., 7, 816-830 (2017)
Using Exalpha's FITC labeled anti PY20 Antibody (Cat. No. X1017)

References

X1592P Sphingosine 1 Phosphate 4 Receptor (IN) (EDG6)
1. Ohotski, J., et al. ‘ Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer.’ British Journal of Cancer, Apr 2012, 106(8): 1453-1459.


X2717B Sphingosine 1 Phosphate 4 Receptor (NT) (EDG6)
1. Ohotski, J., et al. ‘ Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer.’ British Journal of Cancer, Apr 2012, 106(8): 1453-1459.


X1593P Sphingosine 1 Phosphate 4 Receptor (NT) (EDG6) NT
1. Ohotski, J., et al. ‘ Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer.’ British Journal of Cancer, Apr 2012, 106(8): 1453-1459.


X1631P Sphingosine 1-Phosphate Lyase 1
1. Katsuma, Susumu, et al, 'Signalling mechanisms in sphingosine 1-phosphate-promoted mesangial cell proliferation ' Genes to Cells 2002, 7, , 1217-1230


X1627P Sphingosine Kinase 1
1. Manikandan, Jayapal, et al, 'Genome-wide gene expression profiling of human mast cells stimulated by IgE or Fc RI-aggregation reveals a complex network of genes involved in inflammatory responses ' BMC Genomics 2006, 7, 210, Online only
2. Yang, Jianfei, et al., 'Sphingosine Kinase 1 Is a Negative Regulator of CD4 Th1 Cells ' The Journal of Immunology 2005, 175, , 6580-6588
3.El-Shewy, H.M., et al. ‘Low-Density Lipoprotein Induced Expression of Connective Tissue Growth Factor via Transactivation of Sphingosine 1-Phosphate Receptors in Mesangial Cells.’ Molecular Endocrinology, May 2012, 26(5): 833-845.


X1849P Sphingosine Kinase 1,(pS225), Mouse Reactive
1. El-Shewy, H.M., et al. ‘Low-Density Lipoprotein Induced Expression of Connective Tissue Growth Factor via Transactivation of Sphingosine 1-Phosphate Receptors in Mesangial Cells.’ Molecular Endocrinology, May 2012, 26(5): 833-845.


X1072M TCF-1
1. Dorfman, David M. et al., 'Loss of Expression of the WNT/Beta Catenin Signaling Pathway Transcription Factors Lymphoid Enhancer Factor-1 (LEF-1) and T Cell factor-1 (TCF-10 in a Subset of Peripheral T Cel Lymphomas' The American Journal of Pathology 2003, 162, , 1539-1544
2. Tobimatsu, Takako, et al, 'Parathyroid Hormone Increaes Beta Catenin levels through Smad3 in Mouse Osteblastic Cells' Endocrinology 2006, 147, 5, 2583-2590


X1070M TCF-4
1. Sampson, Ellen, M., et al, 'Negative regulation of the Wnt- Beta-Catenin pathway by the transcriptional represor HBPQ' The EMBO Journal 2001, 20, , 4500-4511
2. Uematsu, Kazutsugu, et al, 'Wnt Pathway Activation in Mesothelioma: Evidence of Dishevelled Overexpression and Transcriptional Activity of Beta Catenin' Journal of Cancer Research 2003, 63, , 4547-4551
3. Shimura, Tatsuo, 'Galectin-3, a Novel Binding Partner of Beta Catenin' Cancer Research 2004, 64, , 6363-6367


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