Exalpha Biologicals, Inc.

Product Highlight

FIX&PERM Cell Fixation and Permeabilization Kit

Flow cytometric analyses with monoclonal antibodies were so far mainly restricted to cell surface molecules. Intracellular structures such as cytoplasmic or nuclear enzymes, oncoproteins, cytokines, immunoglobulins etc. were largely excluded from such studies. Also excluded from flow cytometric studies were cytoplasmic localizations of well-established membrane molecules like CD3 and CD22, which, in their cytoplasmic form, are the most reliable lineage markers in undifferentiated leukemia. With the FIX&PERM® Kit flow cytometric analysis of intracellular antigens has become as easy as surface antigen studies. The only prerequisite is the availability of suitable antibody conjugates. Most of the available monoclonal antibody conjugates can be used with the FIX&PERM® Kit, some determinants are sensitive, however, to the fixation step involved. This and the optimal fixation time have to be tested for each reagent.

News

Welcome, Peter Rutten

We are pleased to announce that Peter Rutten has now started in his role as Operations Director here at Exalpha Biologicals Inc. Peter has a Master’s of Science degree in Industrial and Organizational Psychology and this has lead him down a very business orientated career path. Peter is looking forward to working with the team at Exalpha. Peters primary focus is the customer experience and he will be working with the Laboratory team, the Quality Control team and the Order Processing team to ensure this focus is achieved. We all wish Peter well in his new role.

References

X1010 14-3-3 theta/tau
1. Kakinuma, N., et al. ?Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K?Akt signaling.? J. Cell Biol. 2008, 181, 537-549
2. Patel, A., et al. ?Host protein interactions with enteropathogenic Escherichia coli (EPEC): 14-3-3 binds Tir and has a role in EPEC-induced actin polymerization.? Cellular Microbiology, 2006, 8, 55-71


U115P ADAR2 (Adenosine Deaminase Acting on RNA 2)
1. Hideyama, T., et al. ?Co-Occurrence of TDP-43 Mislocalization with Reduced Activity of an RNA Editing Enzyme, ADAR2, in Aged Mouse Motor Neurons? PLoS One, 7, e43469, 2012
2. Yamashita, T., et al. ?Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons.? EMBO Mol. Med., 2013, 5, 1710-1719


X1107P Aif (CT) apoptosis inducing factor
1. Pantic, B., et al. ?Myotonic dystrophy protein kinase (DMPK) prevents ROS-induced cell death by assembling a hexokinase II-Src complex on the mitochondrial surface.? Cell Death and Disease, Oct 2013, 4(10): e858


X1108P Aif (IN) apoptosis inducing factor
1. Pantic, B., et al. ?Myotonic dystrophy protein kinase (DMPK) prevents ROS-induced cell death by assembling a hexokinase II-Src complex on the mitochondrial surface.? Cell Death and Disease, Oct 2013, 4(10): e858


X1109P Aif (NT) apoptosis inducing factor
1. Pantic, B., et al. ?Myotonic dystrophy protein kinase (DMPK) prevents ROS-induced cell death by assembling a hexokinase II-Src complex on the mitochondrial surface.? Cell Death and Disease, Oct 2013, 4(10): e858


X1844K AKT ELISA
1. Yan, B., et al. ?Regulation of PTEN/Akt Pathway Enhances Cardiomyogenesis and Attenuates Adverse Left Ventricular Remodeling following Thymosin 4 Overexpressing Embryonic Stem Cell Transplantation in the Infarcted Heart.? PLoS One, 8, e75580 (2013)


T110M Alx-4
1. Rendl, Michael et al., 'Molecular Dissection of Mesenchymal-Epithelial Interactions in the Hair Follicle' Public Library of Science 2005, 3, 11, e331


A100M bax
1. Annis, M., et al, 'Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis' EMBO Journal 2005, 24, , 2096-2103
2. Soucie, E.L., et al, 'Myc Potentiates Apoptosis by Stimulating Bax Activity at the Mitochondria' Molecular and Cell Biology 2001, 21, , 4725-4736
3. Karch, J., et al. ?Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice.? eLife, 2, e00772 (2013)


A105M bax (universal)
1. Lau, E., et al. ?PKC regulates ATF2 availability to alter mitochondrial permeability following genotoxic stress.? Cell, 148, 543-555 (2012)
2. Cazanave, S.C., et. ?JNK1-dependent PUMA Expression Contributes to
Hepatocyte Lipoapoptosisal.?
3. Akazawa, Y., et al. ?Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis.? PLoS One, 8, e82322 (2013)


X1120P Bnip3L (IN) (nix) (bcl 2 family)
1. Zhang, J., et al. ?A short linear motif in BNIP3L (NIX) mediates mitochondrial clearance in reticulocytes.? Autophagy, 8, 1325-1332 (2012)


A205P BrdU (bromodeoxyuridine)
1. Robert K Dempsey, et al., 'Stroke-induced progenitor cell proliferation in adult spontaneously hypertensive rat brain: effect of exogenoug IGF-1 and GDNF' Journal of Neurochemistry 2003, 87, , 586-597


X1545K BrdU (Bromodeoxyuridine)
1. Sato, S., et al, 'Central control of bone remodeling by neuromedin U' Nature Medicine 2007, 13, , 1234-1240


X2839K BrdU (Bromodeoxyuridine), FL488
1. Sato, S., et al, 'Central control of bone remodeling by neuromedin U' Nature Medicine 2007, 13, , 1234-1240


X2840K BrdU (Bromodeoxyuridine), FL549
1. Sato, S., et al, 'Central control of bone remodeling by neuromedin U' Nature Medicine 2007, 13, , 1234-1240


X1327K1 BrdU Cell Proliferation
1. Chang, V., et al, 'Adenoviral-mediated gene transfer of ectodysplasin-A2 results in induction of apoptosis and cell-cycle arrest in osteosarcoma cell lines.' Cancer Gene Therapy 2007, 14, , 927-933
2. Sekine, C., et al, 'Successful Treatment of Animal Models of Rheumatoid Arthritis with Small-Molecule Cyclin-Dependent Kinase Inhibitors' Journal of Immunology 2008, 180, , 1954-1961
3. Matta, H., et al, 'Activation of alternative NF- B pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 -converting enzyme inhibitory protein (vFLIP)' PNAS 2004, 101, , 9399-9404
4. Manov, I., et al. ?Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitro evidence.? BMC Biol., 2013, 11, 91
5. Sharvit, E., et al. ?Amplified Inhibition of Stellate Cell Activation Pathways by PPAR- , RAR and RXR Agonists.? PLoS One, 2013, 8, e76541
6. Lenarduzzi, M., et al. ?Hemochromatosis Enhances Tumor Progression via Upregulation of Intracellular Iron in Head and Neck Cancer.? PLoS One, 2013, 8, e74075
7. Vishwamitra, D., et al. ?MicroRNA 96 Is a Post-Transcriptional Suppressor of Anaplastic Lymphoma Kinase Expression.? Am. J. Pathol., 2012, 180, 1772-1780
8. Shirin, H., et al. ?Atorvastatin and rosuvastatin do not prevent thioacetamide induced liver cirrhosis in rats.? World J. Gastroenterol., 2013, 19, 241-248
9. Li, L.-D., et al. ?Effect of active immunization against angiotensin II type 1 (AT1) receptor on hypertension & arterial remodelling in spontaneously hypertensive rats (SHR)? Indian J. Med. Res. 2014, 139, 619-624
10, Gutschalk, C.M., et al. ?GM-CSF enhances tumor invasion by elevated MMP-2, -9, and -26 expression? Cancer Med. 2013, 2, 117-129
11. Boonanantanasam, K., et al. ?Enterococcus faecalis Enhances Cell Proliferation through Hydrogen Peroxide-Mediated Epidermal Growth Factor Receptor Activation? Infect. Immun. 2012, 80, 3545-3558


X1327K2 BrdU Cell Proliferation
1. Chang, V., et al, 'Adenoviral-mediated gene transfer of ectodysplasin-A2 results in induction of apoptosis and cell-cycle arrest in osteosarcoma cell lines.' Cancer Gene Therapy 2007, 14, , 927-933
2. Sekine, C., et al, 'Successful Treatment of Animal Models of Rheumatoid Arthritis with Small-Molecule Cyclin-Dependent Kinase Inhibitors' Journal of Immunology 2008, 180, , 1954-1961
3. Matta, H., et al, 'Activation of alternative NF- B pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 -converting enzyme inhibitory protein (vFLIP)' PNAS 2004, 101, , 9399-9404
4. Manov, I., et al. ?Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitro evidence.? BMC Biol., 2013, 11, 91
5. Sharvit, E., et al. ?Amplified Inhibition of Stellate Cell Activation Pathways by PPAR- , RAR and RXR Agonists.? PLoS One, 2013, 8, e76541
6. Lenarduzzi, M., et al. ?Hemochromatosis Enhances Tumor Progression via Upregulation of Intracellular Iron in Head and Neck Cancer.? PLoS One, 2013, 8, e74075
7. Vishwamitra, D., et al. ?MicroRNA 96 Is a Post-Transcriptional Suppressor of Anaplastic Lymphoma Kinase Expression.? Am. J. Pathol., 2012, 180, 1772-1780
8. Shirin, H., et al. ?Atorvastatin and rosuvastatin do not prevent thioacetamide induced liver cirrhosis in rats.? World J. Gastroenterol., 2013, 19, 241-248
9. Li, L.-D., et al. ?Effect of active immunization against angiotensin II type 1 (AT1) receptor on hypertension & arterial remodelling in spontaneously hypertensive rats (SHR)? Indian J. Med. Res. 2014, 139, 619-624
10, Gutschalk, C.M., et al. ?GM-CSF enhances tumor invasion by elevated MMP-2, -9, and -26 expression? Cancer Med. 2013, 2, 117-129
11. Boonanantanasam, K., et al. ?Enterococcus faecalis Enhances Cell Proliferation through Hydrogen Peroxide-Mediated Epidermal Growth Factor Receptor Activation? Infect. Immun. 2012, 80, 3545-3558


X1327K3 BrdU Cell Proliferation
1. Chang, V., et al, 'Adenoviral-mediated gene transfer of ectodysplasin-A2 results in induction of apoptosis and cell-cycle arrest in osteosarcoma cell lines.' Cancer Gene Therapy 2007, 14, , 927-933
2. Sekine, C., et al, 'Successful Treatment of Animal Models of Rheumatoid Arthritis with Small-Molecule Cyclin-Dependent Kinase Inhibitors' Journal of Immunology 2008, 180, , 1954-1961
3. Matta, H., et al, 'Activation of alternative NF- B pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 -converting enzyme inhibitory protein (vFLIP)' PNAS 2004, 101, , 9399-9404
4. Manov, I., et al. ?Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitro evidence.? BMC Biol., 2013, 11, 91
5. Sharvit, E., et al. ?Amplified Inhibition of Stellate Cell Activation Pathways by PPAR- , RAR and RXR Agonists.? PLoS One, 2013, 8, e76541
6. Lenarduzzi, M., et al. ?Hemochromatosis Enhances Tumor Progression via Upregulation of Intracellular Iron in Head and Neck Cancer.? PLoS One, 2013, 8, e74075
7. Vishwamitra, D., et al. ?MicroRNA 96 Is a Post-Transcriptional Suppressor of Anaplastic Lymphoma Kinase Expression.? Am. J. Pathol., 2012, 180, 1772-1780
8. Shirin, H., et al. ?Atorvastatin and rosuvastatin do not prevent thioacetamide induced liver cirrhosis in rats.? World J. Gastroenterol., 2013, 19, 241-248
9. Li, L.-D., et al. ?Effect of active immunization against angiotensin II type 1 (AT1) receptor on hypertension & arterial remodelling in spontaneously hypertensive rats (SHR)? Indian J. Med. Res. 2014, 139, 619-624
10, Gutschalk, C.M., et al. ?GM-CSF enhances tumor invasion by elevated MMP-2, -9, and -26 expression? Cancer Med. 2013, 2, 117-129
11. Boonanantanasam, K., et al. ?Enterococcus faecalis Enhances Cell Proliferation through Hydrogen Peroxide-Mediated Epidermal Growth Factor Receptor Activation? Infect. Immun. 2012, 80, 3545-3558


X1114P Caspase-12 (IN)
1. Hetz, C., et al, 'Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein' EMBO Journal 2003, 22, , 5435-54
2. Hetz, C., et al, 'The Disulfide Isomerase Grp58 Is a Protective Factor against Prion Neurotoxicity' Journal of Neuroscience 2005, 25, , 2793-2802
3. Rao, Rammohan V., et al, 'Coupling Endoplasmic Reticulum Stress to the Cell Death Program' The Journal of Biological Chemistry 2002, 277, 24, 21836-21842
4. Moreno, J.A., et al. ?Sustained translational repression by eIF2 ?P mediates prion neurodegeneration.? Nature, 485, 507-511 (2012)
5. Sun, W., et al. ?Magnolia Extract (BL153) Protection of Heart from Lipid Accumulation Caused Cardiac Oxidative Damage, Inflammation, and Cell Death in High-Fat Diet Fed Mice? Oxid. Med. Cell. Longev. (2014), 205849
6. Zhao, Y., et al. ?A Novel Mechanism by Which SDF-1 Protects Cardiac Cells From Palmitate-Induced Endoplasmic Reticulum Stress and Apoptosis via CXCR7 and AMPK/p38 MAPK-Mediated Interleukin-6 Generation? Diabetes (2013), 62, 2545-2558


X1115P Caspase-12 (NT) (involved in Alzheimers)
1. Hetz, C., et al, 'Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein' EMBO Journal 2003, 22, , 5435-54
2. Hetz, C., et al, 'The Disulfide Isomerase Grp58 Is a Protective Factor against Prion Neurotoxicity' Journal of Neuroscience 2005, 25, , 2793-2802
3. Rao, Rammohan V., et al, 'Coupling Endoplasmic Reticulum Stress to the Cell Death Program' The Journal of Biological Chemistry 2002, 277, 24, 21836-21842
4. Moreno, J.A., et al. ?Sustained translational repression by eIF2 ?P mediates prion neurodegeneration.? Nature, 485, 507-511 (2012)
5. Sun, W., et al. ?Magnolia Extract (BL153) Protection of Heart from Lipid Accumulation Caused Cardiac Oxidative Damage, Inflammation, and Cell Death in High-Fat Diet Fed Mice? Oxid. Med. Cell. Longev. (2014), 205849
6. Zhao, Y., et al. ?A Novel Mechanism by Which SDF-1 Protects Cardiac Cells From Palmitate-Induced Endoplasmic Reticulum Stress and Apoptosis via CXCR7 and AMPK/p38 MAPK-Mediated Interleukin-6 Generation? Diabetes (2013), 62, 2545-2558


0141 CD14
1. Cappelli, G., et al, 'Human Macrophage Gamma Interferon Decreases Gene Expression but Not Replication of Mycobacterium tuberculosis: Analysis of the Host-Pathogen Reciprocal Influence on Transcription in a Comparison of Strains H37Rv and CMT97' Infectious Immunology 2001, 69, , 7262-7270


0144 CD14 PE
1. Takebayashi, M., et al, 'Blood dendritic cells are decreased in acute graft-versus-host disease' Bone Marrow Transplantation 2004, 33, , 989-996


0162 CD16 FITC
1. Tajima, Kenichirou et al, 'Immunomodulatory effects of cyclosporin A on human perioheral blood dendritic cell subsets' Immunology 2003, 108, 3, 321


0164 CD16 PE
1. Takebayashi, M., et al, 'Blood dendritic cells are decreased in acute graft-versus-host disease' Bone Marrow Transplantation 2004, 33, , 989-996


0194 CD19 PE
1. Takebayashi, M., et al, 'Blood dendritic cells are decreased in acute graft-versus-host disease' Bone Marrow Transplantation 2004, 33, , 989-996


0032 CD3 FITC
1. Tajima, Kenichirou et al, 'Immunomodulatory effects of cyclosporin A on human perioheral blood dendritic cell subsets' Immunology 2003, 108, 3, 321


0034 CD3 PE
1. Takebayashi, M., et al, 'Blood dendritic cells are decreased in acute graft-versus-host disease' Bone Marrow Transplantation 2004, 33, , 989-996


AP04 CD4 APC
1. Chakrabarti, L.A., et al, 'Normal T-Cell Turnover in Sooty Mangabeys Harboring Active Simian Immunodeficiency Virus Infection' Journal of Virology 2000, 74, , 1209-1223


0042 CD4 FITC
1. Tajima, Kenichirou et al, 'Immunomodulatory effects of cyclosporin A on human perioheral blood dendritic cell subsets' Immunology 2003, 108, 3, 321


0044 CD4 PE
1. O'Neill, E., et al, 'Dynamic Evolution of the Human Immunodeficiency Virus Type 1 Pathogenic Factor, Nef' Journal of Virology 2006, 80, 3, 1311-1320
2. Foster, J.L., et al, 'Genetic and Functional Diversity of Human Immunodeficiency Virus Type 1 Subtype B Nef Primary Isolates' Journal of Virology 2001, 75, , 1672-1680
3. Goldstein, S., et al, 'Plateau Levels of Viremia Correlate with the Degree of CD4+-T-Cell Loss in Simian Immunodeficiency Virus SIVagm-Infected Pigtailed Macaques: Variable Pathogenicity of Natural SIVagm Isolates' Journal of Virology 2005, 79, , 5153-5162
4. Chakrabarti, L.A., et al, 'A Truncated Form of Nef Selected during Pathogenic Reversion of Simian Immunodeficiency Virus SIVmac239{Delta}nef Increases Viral Replication' Journal of Virology 2003, 77, , 1234-1256
5. Chakrabarti, L.A., et al, 'Properties of the Surface Envelope Glycoprotein Associated with Virulence of Simian-Human Immunodeficiency Virus SHIVSF33A Molecular Clones' Journal of Virology 2002, 76, , 1588-1599
6. Luo, T., et al., 'Human Immunodeficiency Virus Type 1 Nef-Induced CD4 Cell Surface Downregulation Is Inhibited by Ikarugamycin' Journal of Virology 2001, 75, , 2488-2492
7. Anderson, S.J., et al, 'The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef' Journal of Virology 1994, 68, , 3092-3101
8. Kuo, L.S., et al. ?Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix.? Retrovirology, 9, 47 (2012)


42A4 CD42a PE
1. Heilmann, C., et al, 'Staphylococcus aureus Fibronectin-Binding Protein (FnBP)?Mediated Adherence to Platelets, and Aggregation of Platelets Induced by FnBPA but Not by FnBPB' Journal of Infectious Disease 2004, 190, , 321-329


0541 CD54
1. Masakazu Nagafuku, et al, 'Reduction of Glycosphingolipid Levels in Lipid Rafts Affects the Expression State and Function of Glycosylphosphatidylinositol-anchored Proteins but Does Not Impair Signal Transduction via the T Cell Receptor' Journal of Biological Chemistry 2003, 278, 51, 51920-51927


0544 CD54 PE
1. Arpinati, M., et al, 'Use of anti-BDCA-2 antibody for detection of dendritic cells type-2 (DC2) in allogeneic hematopoietic stem cell transplantation' Bone Marrow Transplantation 2002, 29, , 887-891


0561 CD56
1. Horikawa, M., et al, 'Abnormal Natural Killer Cell Function in Systemic Sclerosis: Altered Cytokine Production and Defective Killing Activity' Journal of Investigative Dermatology 2005, 125, , 731-737
2. Ishimoto, H., et al, 'Midkine, a heparin-binding growth factor, selectively stimulates proliferation of definitive zone cells of the human fetal adrenal gland' Journal of Endocrinol. Metab 2006, 91, , 4050-4056
3. Muench, M., et al, 'Isolation of Definitive Zone and Chromaffin Cells Based upon Expression of CD56 (Neural Cell Adhesion Molecule) in the Human Fetal Adrenal Gland' Journal of Clinical Endocrinol. Metab 2003, 88, , 3921-3930
4. Miles, L.A., et al, 'Cell-Surface Actin Binds Plasminogen and Modulates Neurotransmitter Release from Catecholaminergic Cells' Journal of Neuroscience 2006, 26, , 13017-13024


0081 CD8
1. Kawabata, S., et al, 'Induction of Th2 Cytokine Expression for p27-Specific IgA B Cell Responses after Targeted Lymph Node Immunization with Simian Immunodeficiency Virus Antigens in Rhesus Macaques' Journal of Infectious Disease 1998, 177, , 26-33


AP08 CD8 APC
1. Chakrabarti, L.A., et al, 'Normal T-Cell Turnover in Sooty Mangabeys Harboring Active Simian Immunodeficiency Virus Infection' Journal of Virology 2000, 74, , 1209-1223


0084 CD8 PE
1. Sauermann, U., et al, 'Homozygosity for a Conserved Mhc Class II DQ-DRB Haplotype Is Associated with Rapid Disease Progression in Simian Immunodeficiency Virus?Infected Macaques: Results from a Prospective Study' Journal of Infectious Disease 2000, 182, , 716-724


X1700P Ceramide Glycosyltransferase
1. D'Angelo, G., et a, 'Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide.' Nature 2007, 449, , 62-67


X2161P Ceramide kinase (CERK) (NT)
1. Barth, B.M., et al. ?Ceramide Kinase Regulates TNF -Stimulated NADPH Oxidase Activity and Eicosanoid Biosynthesis in Neuroblastoma Cells? Cell Signal. (2012), 24, 1126-1133


X2160P Ceramide kinase (CERK) (IN)
1. Barth, B.M., et al. ?Ceramide Kinase Regulates TNF -Stimulated NADPH Oxidase Activity and Eicosanoid Biosynthesis in Neuroblastoma Cells? Cell Signal. (2012), 24, 1126-1133


X1179P chx 10 (Visual system homeobox 2) (CT)
1. Qiu, F., et al, 'A Comprehensive Negative Regulatory Program Controlled by Brn3b to Ensure Ganglion Cell Specification from Multipotential Retinal Precursors' Journal of Neuroscience (2008), 28, , 3392-3403
2. Elshatory, Y., et a, 'Islet-1 Controls the Differentiation of Retinal Bipolar and Cholinergic Amacrine Cells' Journal of Neuroscience (2007), 27, , 12707-12720
3. Osakada, F., et al, 'Wnt Signaling Promotes Regeneration in the Retina of Adult Mammals' Journal of Neuroscience (2007), 27, , 4210-4219
4. Nittner, D., et al. 'Synthetic lethality between Rb, p53 and Dicer or miR-17?92 in retinal progenitors suppresses retinoblastoma formation.' Nature Cell Biology (2012), 14, 958?965
5. Tiwari, S., et al. ?Meckelin 3 Is Necessary for Photoreceptor Outer Segment Development in Rat Meckel Syndrome.? PLoS One, 8, e59306 (2013)
6. Sherry, D.M., et al. ?Differential Developmental Deficits in Retinal Function in the Absence of either Protein Tyrosine Sulfotransferase-1 or -2.? PLoS One, 7, e39702 (2012)
7. Luo, H., et al. ?Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors.? Proc. Natl. Acad. Sci. USA, 109, E553-E562 (2012)
8. Haynes, T., et al. ?Complement anaphylatoxin C3a is a potent inducer of embryonic chick retina regeneration.? Nat. Commun. 4, 2312 (2013)
9. Wakabayashi, T., et al. ?Prolonged Expression of Puma in Cholinergic Amacrine Cells During the Development of Rat Retina.? J. Histochem. Cytochem., 60, 777-788 (2012)
10. Bai, L., et al. ?Birth of Cone Bipolar Cells, but Not Rod Bipolar Cells, Is Associated with Existing RGCs.? PLoS One, 9, e83686 (2014)
11. Nakano, T., et al. ?Self-formation of optic cups and storable stratified neural retina from human ESCs.? Cell Stem Cell (2012) 10, 771-785
12. Huang, L., et al. ?Bhlhb5 is Required for the Subtype Development of Retinal Amacrine and Bipolar Cells in Mice? Dev. Dyn. (2014), 243, 279-289
13. Wang, W., et al. ?Swine Cone and Rod Precursors Arise Sequentially and Display Sequential and Transient Integration and Differentiation Potential Following Transplantation? Invest. Ophthalmol. Vis. Sci., (2014), 55, 301-309
14. Voinescu, P.E., et al. ?Birthdays of retinal amacrine cell subtypes are systematically related to their molecular identity and soma position? J. Comp. Neurol., (2009), 517, 737
15. Roy, A., et al. ?Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification? Development, (2012), 139, 3109-3119
16. Prasov, L., et al. ?Pushing the envelope of retinal ganglion cell genesis: context dependent function of Math5 (Atoh7)? Dev. Biol. (2012), 368, 214-230
17. Jiang, Y., et al. ?Transcription Factors SOX4 and SOX11 Function Redundantly to Regulate the Development of Mouse Retinal Ganglion Cells? J. Biol. Chem. (2013), 288, 18429-18438
18. Hufnagel, R.B., et al. ?Heterochronic misexpression of Ascl1 in the Atoh7 retinal cell lineage blocks cell cycle exit? Mol. Cell Neurosci. (2013), 54, 108-120
19. Firl, A., et al. ?Extrasynaptic glutamate and inhibitory neurotransmission modulate ganglion cell participation during glutamatergic retinal waves? J. Neurophysiol. (2013), 109, 1969-1978
20. Bassett, E.A., et al. ?Overlapping Expression Patterns and Redundant Roles for AP-2 Transcription Factors in the Developing Mammalian Retina? Dev. Dyn. (2012), 24, 814-829


X1180P chx 10 (Visual system homeobox 2) (NT)
1. Qiu, F., et al, 'A Comprehensive Negative Regulatory Program Controlled by Brn3b to Ensure Ganglion Cell Specification from Multipotential Retinal Precursors' Journal of Neuroscience (2008), 28, , 3392-3403
2. Elshatory, Y., et a, 'Islet-1 Controls the Differentiation of Retinal Bipolar and Cholinergic Amacrine Cells' Journal of Neuroscience (2007), 27, , 12707-12720
3. Osakada, F., et al, 'Wnt Signaling Promotes Regeneration in the Retina of Adult Mammals' Journal of Neuroscience (2007), 27, , 4210-4219
4. Nittner, D., et al. 'Synthetic lethality between Rb, p53 and Dicer or miR-17?92 in retinal progenitors suppresses retinoblastoma formation.' Nature Cell Biology (2012), 14, 958?965
5. Tiwari, S., et al. ?Meckelin 3 Is Necessary for Photoreceptor Outer Segment Development in Rat Meckel Syndrome.? PLoS One, 8, e59306 (2013)
6. Sherry, D.M., et al. ?Differential Developmental Deficits in Retinal Function in the Absence of either Protein Tyrosine Sulfotransferase-1 or -2.? PLoS One, 7, e39702 (2012)
7. Luo, H., et al. ?Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors.? Proc. Natl. Acad. Sci. USA, 109, E553-E562 (2012)
8. Haynes, T., et al. ?Complement anaphylatoxin C3a is a potent inducer of embryonic chick retina regeneration.? Nat. Commun. 4, 2312 (2013)
9. Wakabayashi, T., et al. ?Prolonged Expression of Puma in Cholinergic Amacrine Cells During the Development of Rat Retina.? J. Histochem. Cytochem., 60, 777-788 (2012)
10. Bai, L., et al. ?Birth of Cone Bipolar Cells, but Not Rod Bipolar Cells, Is Associated with Existing RGCs.? PLoS One, 9, e83686 (2014)
11. Nakano, T., et al. ?Self-formation of optic cups and storable stratified neural retina from human ESCs.? Cell Stem Cell (2012) 10, 771-785
12. Huang, L., et al. ?Bhlhb5 is Required for the Subtype Development of Retinal Amacrine and Bipolar Cells in Mice? Dev. Dyn. (2014), 243, 279-289
13. Wang, W., et al. ?Swine Cone and Rod Precursors Arise Sequentially and Display Sequential and Transient Integration and Differentiation Potential Following Transplantation? Invest. Ophthalmol. Vis. Sci., (2014), 55, 301-309
14. Voinescu, P.E., et al. ?Birthdays of retinal amacrine cell subtypes are systematically related to their molecular identity and soma position? J. Comp. Neurol., (2009), 517, 737
15. Roy, A., et al. ?Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification? Development, (2012), 139, 3109-3119
16. Prasov, L., et al. ?Pushing the envelope of retinal ganglion cell genesis: context dependent function of Math5 (Atoh7)? Dev. Biol. (2012), 368, 214-230
17. Jiang, Y., et al. ?Transcription Factors SOX4 and SOX11 Function Redundantly to Regulate the Development of Mouse Retinal Ganglion Cells? J. Biol. Chem. (2013), 288, 18429-18438
18. Hufnagel, R.B., et al. ?Heterochronic misexpression of Ascl1 in the Atoh7 retinal cell lineage blocks cell cycle exit? Mol. Cell Neurosci. (2013), 54, 108-120
19. Firl, A., et al. ?Extrasynaptic glutamate and inhibitory neurotransmission modulate ganglion cell participation during glutamatergic retinal waves? J. Neurophysiol. (2013), 109, 1969-1978
20. Bassett, E.A., et al. ?Overlapping Expression Patterns and Redundant Roles for AP-2 Transcription Factors in the Developing Mammalian Retina? Dev. Dyn. (2012), 24, 814-829


X1789P Collapsin response mediator protein 1 (CT)
1. Nilsen, J., et al, Estradiol In Vivo Regulation of Brain Mitochondrial Proteome, Journal of Neuroscience 2007, 27, , 14069-14077


X1790P Collapsin response mediator protein 1 (IN)
1. Nilsen, J., et al, Estradiol In Vivo Regulation of Brain Mitochondrial Proteome Journal of Neuroscience 2007, 27, , 14069-14077


A090M COX II (cyclooxygenase II)
1. Kaneshiro, Y., et al, 'Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats' Kidney International 2006, 70, , 641-646


X1588P DAP12
1. Zou, W., et al, 'DAP12 Couples c-Fms activation to the osteoclast cytoskeleton by recruitment of Syk' Molecultar Cell 2008, 31, 3, 422-431


U100P Disabled (NT)
1. Cuchillo-Ibanez, I., et al. ?Beta-Amyloid Impairs Reelin Signaling.? PLoS One, 8, e72297 (2013)


F115P EBNA 3A
1. Anderton, E., et al, 'Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma' Oncogene 2007, 27, , 421-433
2. O'Nions, J., et al, 'Epstein?Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2' Oncogene 2003, 22, , 7181-7191
3. Jiménez-Ramírez, C., et al, 'Epstein-Barr Virus EBNA-3C Is Targeted to and Regulates Expression from the Bidirectional LMP-1/2B Promoter' Journal of Virology 2006, 80, , 11200-11208
4. Yuan, J., et al, 'Virus and Cell RNAs Expressed during Epstein-Barr Virus Replication' Journal of Virology 2006, 80, , 2548-2565
5. Hong, G.K., et al, 'Epstein-Barr Virus Lytic Infection Contributes to Lymphoproliferative Disease in a SCID Mouse Model' Journal of Virology 2005, 79, , 13993-14003
6. Rosendorff, A., et al, 'EBNA3C Coactivation with EBNA2 Requires a SUMO Homology Domain' Journal of Virology 2004, 78, , 367-377
7. Maruo, S., et al, 'Epstein-Barr Virus Nuclear Protein EBNA3A Is Critical for Maintaining Lymphoblastoid Cell Line Growth' Journal of Virology 2003, 77, , 10437-10447
8. Dalbi


F120P EBNA 3B
1. Anderton, E., et al, 'Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma' Oncogene 2007, 27, , 421-433
2. O'Nions, J., et al, 'Epstein?Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2' Oncogene 2003, 22, , 7181-7191
3. Jiménez-Ramírez, C., et al, 'Epstein-Barr Virus EBNA-3C Is Targeted to and Regulates Expression from the Bidirectional LMP-1/2B Promoter' Journal of Virology 2006, 80, , 11200-11208
4. Yuan, J., et al, 'Virus and Cell RNAs Expressed during Epstein-Barr Virus Replication' Journal of Virology 2006, 80, , 2548-2565
5. Hong, G.K., et al, 'Epstein-Barr Virus Lytic Infection Contributes to Lymphoproliferative Disease in a SCID Mouse Model' Journal of Virology 2005, 79, , 13993-14003
6. Rosendorff, A., et al, 'EBNA3C Coactivation with EBNA2 Requires a SUMO Homology Domain' Journal of Virology 2004, 78, , 367-377
7. Maruo, S., et al, 'Epstein-Barr Virus Nuclear Protein EBNA3A Is Critical for Maintaining Lymphoblastoid Cell Line Growth' Journal of Virology 2003, 77, , 10437-10447
8. Gordadze, A.V., et al, 'Notch1IC Partially Replaces EBNA2 Function in B Cells Immortalized by Epstein-Barr Virus' Journal of Virology 2001, 75, , 5899-5912
9. McClellan, M.J., et al. ?Downregulation of Integrin Receptor-Signaling Genes by Epstein-Barr Virus EBNA 3C via Promoter-Proximal and -Distal Binding Elements? J. Virol. (2012), 86(9):5165-5178


F125P EBNA 3C
1. Anderton, E., et al, 'Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma' Oncogene 2007, 27, , 421-433
2. O'Nions, J., et al, 'Epstein?Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2' Oncogene 2003, 22, , 7181-7191
3. Jiménez-Ramírez, C., et al, 'Epstein-Barr Virus EBNA-3C Is Targeted to and Regulates Expression from the Bidirectional LMP-1/2B Promoter' Journal of Virology 2006, 80, , 11200-11208
4. Yuan, J., et al, 'Virus and Cell RNAs Expressed during Epstein-Barr Virus Replication' Journal of Virology 2006, 80, , 2548-2565
5. Hong, G.K., et al, 'Epstein-Barr Virus Lytic Infection Contributes to Lymphoproliferative Disease in a SCID Mouse Model' Journal of Virology 2005, 79, , 13993-14003
6. Rosendorff, A., et al, 'EBNA3C Coactivation with EBNA2 Requires a SUMO Homology Domain' Journal of Virology 2004, 78, , 367-377
7. Maruo, S., et al, 'Epstein-Barr Virus Nuclear Protein EBNA3A Is Critical for Maintaining Lymphoblastoid Cell Line Growth' Journal of Virology 2003, 77, , 10437-10447
8. Gordadze, A.V., et al, 'Notch1IC Partially Replaces EBNA2 Function in B Cells Immortalized by Epstein-Barr Virus' Journal of Virology 2001, 75, , 5899-5912
9. Homa, N.J., et al. ?Epstein-Barr Virus Induces Global Changes in Cellular mRNA Isoform Usage That Are Important for the Maintenance of Latency.? Journal of Virology, Nov 2013, 87(22): 12291-12301


X1266M Estrogen Receptor
1. Schuler, G., et al. ?Occurrence of estrogen receptor alpha in bovine placentomes throughout mid and late gestation and at parturition.? Biol. Reprod. (2012), 66, 976-982
2. Santeusanio, G., et al. ?Immunohistochemical analysis of estrogen receptors in breast carcinomas using monoclonal antibodies that recognize different domains of the receptor molecule.? Appl. Immunohistochem. Mol. Morphol. (2000), 8, 275-284
3. Hori, M., et al. ?Determination of estrogen receptor in primary breast cancer using two different monoclonal antibodies, and correlation with its mRNA expression.? Pathol. Int. (1999), 49, 191-197
4. Huang, A., et al. ?Immunohistochemical assay for oestrogen receptors in paraffin wax sections of breast carcinoma using a new monoclonal antibody.? J. Pathol. (1996), 180, 223-227


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