Periodic Acid Schiff Protocol

Periodic Acid Schiff Protocol PRINCIPLE:  This type of staining is used for the detection of glycogen. Tissue sections are first oxidized by 0.5% periodic acid solution. The oxidative process results in the formation of aldehyde groupings through carbon-to-carbon bond cleavage. Free hydroxyl groups should be present for oxidation to take place. Oxidation is completed when it reaches the aldehyde and … Continue reading Periodic Acid Schiff Protocol