Exalpha Biologicals, Inc.

Latest News

Exalpha Biologicals, Inc. is now a US distributor for Nordic-Mubio products

Nordic-MUbio develops and manufactures high quality antibody reagents for use in R&D. All our products are manufactured according to strict ISO 9001 quality guidelines, and our focus is on developing antibodies targetting Cell Adhesion, Nuclear and Cytoskeletal Proteins.

Nordic-MUbio is one of the leading antibody companies developing antibodies for zebrafish research – we currently have over 50 antibodies validated for immunofluorescence in zebrafish.

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Latest References

Akazawa, Y., et al. "Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis" PLoS ONE 8(12): e82322

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Homa, N.J., et al. "Epstein-Barr Virus Induces Global Changes in Cellular mRNA Isoform Usage That Are Important for the Maintenance of Latency" J. Virol., 2013, 87, 12291-12301

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Frontier™ ApoMark DNA Fragmentation Detection Kit

Exalpha's Frontier™ ApoMark™ DNA Fragmentation Detection Kit is a non-isotopic system for the labeling of DNA breaks in apoptotic cell nuclei in paraffin-embedded tissue sections, tissue cryosections and in cell preparations fixed on slides. Available using DAB substrate for visualization as well as fluroescent conjugates for immunofluorescence assays


Features

  • All reagents in dropper bottles prediluted and ready to use
  • All buffers and enzymes necessary for staining included
  • Can be used on tissue from any species
  • Streptavidin-Biotin detection system

Ordering Information

  • X2044K1 - 30 tests
  • X2044K2 - 60 tests
  • For larger quantity pricing, please contact customer service.

Legend:
ApoMark™ kit (X2044K) using paraffin fixed human tonsil tissue, 10 μm sections (1000X). A] Section processed and counter-stained with methyl green according to the ApoMark™ manual. B] Counter-stain step was eliminated to more clearly illustrate the level of positive staining in the germinal centers of tonsil tissue. C] Section treated with DNase I in order to generate a positive control slide. Note all nuclei stain positive. The use of DNase I generates free 3’-OH groups on cellular DNA, these free 3’-OH groups are then labeled with biotin-nucleotide by the TdT in the ApoMark™ kit. D] Negative control, the TdT enzyme step was eliminated thereby generating a negative slide.