Rabbit anti Human Protein Phosphatase 2 A/B gammaCatalog number: P180P
Protein phosphatase 2A (PP2A) is a hetertrimeric enzyme consisting of a catalytic subunits (C), a structural subunit (A) and a variable regulatory subunit (B). The B subunit family is made up of the , and isoforms. The PP2A/B isoform appears to only be detectable in the brain where it has been speculated that it cytoskeletal substrates. The RNA which produces the PP2A/B is developmentally regulated and increases sharply after birth. It has also been suggested that it may be important in the establishment and maintenance of neuronal connections.
Synonyms: Protein Phosphatase 2 A/Bγ2
Immunogen: Antibody raised against synthetic peptide corresponding to amino acids 53 to 66 of the mammalian protein phosphatase 2 A/B conjugated to KLH.
Product Form: Unconjugated
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purification Method: Ammonium Sulfate Precipitation
Concentration: See vial for concentration
Detects PP2A/B isoforms by Western blot analysis. Detects a 56 kDa band in whole rat brain homogenates. Optimal concentration should be evaluated by serial dilutions.
Functional Analysis: Western Blotting
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
Product Stability: See expiration date on vial
Shipping Conditions: Ship at ambient temperature, freeze upon arrival
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Exalpha Biologicals accepts no liability for any inaccuracies or omissions in this information.
1. Strack, S., et al. Brain protein phosphatase 2A: Developmental regulation and distinct cellular and subcellular localization by B subunits. J. Comp. Neurol. 1998, 392, 515-527
Database Name: UniProt
Accession Number: Q13362 (Human)P97888 (Rat)Q8BG02 (Mouse)
Species Accession: Human, Rat, Mouse
Safety Datasheet(s) for this product:
Rabbit anti Human Protein Phosphatase 2 A/B gamma
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|"Western blot analysis using anti-PP2A/Bγ2 antibody on total rat brain homogenate with control peptide (1) and blocking peptide (2)."|
"Western blot analysis using anti-PP2A/Bγ2 antibody on total rat brain homogenate with control peptide (1) and blocking peptide (2)."