Monocarboxylate Transport 2Catalog number: X2372B
Functions as a proton-linked monocarboxylate transporter and catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a very high affinity pyruvate transporter. MCT2 is a cell membrane; Multi-pass membrane protein with high expression in testis, moderate to low expression in spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocytes. The normal expression of MCT2 is restricted to low levels of expression in normal tissues, but is widely expressed in cancer cells.
Synonyms: MCT2; Solute carrier family 16 member 7; SLC16A7
Immunogen: Peptide Immunogen
Product Form: Unconjugated
Formulation: Provided as solution in phosphate buffered saline
Concentration: See vial for concentration
For use with Monocarboxylate Transport 2 polyclonal antibodies (Cat. No. X2368P & X2371P).
Functional Analysis: Western Blotting
Positive Control: Testis, spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocyte.
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
Product Stability: See expiration date on vial
Shipping Conditions: Ship at ambient temperature, freeze upon arrival
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Exalpha Biologicals accepts no liability for any inaccuracies or omissions in this information.
1: Dao L., Landschulz W.H., Landschulz K.T.; Cloning of human monocarboxylate transporter 2 (hMCT2). Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases. 2: Lin R.-Y., Vera J.C., Chaganti R.S.K., Golde D.W.; Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter.; J. Biol. Chem. 273:28959-28965(1998).
Database Name: UniProt
Accession Number: O60669 (Human)
Species Accession: Human
Monocarboxylate Transport 2
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