Exalpha Biologicals, Inc.

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Exalpha Biologicals, Inc. is now a US distributor for Nordic-Mubio products

Nordic-MUbio develops and manufactures high quality antibody reagents for use in R&D. All our products are manufactured according to strict ISO 9001 quality guidelines, and our focus is on developing antibodies targetting Cell Adhesion, Nuclear and Cytoskeletal Proteins.

Nordic-MUbio is one of the leading antibody companies developing antibodies for zebrafish research – we currently have over 50 antibodies validated for immunofluorescence in zebrafish.

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Latest References

Akazawa, Y., et al. "Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis" PLoS ONE 8(12): e82322

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Homa, N.J., et al. "Epstein-Barr Virus Induces Global Changes in Cellular mRNA Isoform Usage That Are Important for the Maintenance of Latency" J. Virol., 2013, 87, 12291-12301

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Exalpha Biologicals, Inc.

c-myc

  • Product Code: n115m
  • Size: 100 µg
  • Availability: In Stock In Stock
  • Price (USD): $244

Cat #

n115m		 Quantity:      

Product Name

c- myc

Synonyms

cmyc; Myc proto-oncogene protein; transcription factor p64

Host/Source

Mouse

Clone

33

Isotype

IgG1

Product Type

Monoclonal Antibody

Reactivity

Human, Mouse, Avian

Applications

Western Blot, Immunoprecipitation, Immunohistochemistry

Purification

Protein A/G Chromatography

Size

100 µg

Price (USD)

$244

Background

Human c-myc belongs to a family of 5 myc oncogenes. Amplification of c-myc has been found in several types of human tumors including breast and colon carcinomas. Induction of c-myc in cells grown in the appropriate growth factors or co-expression with survival genes, such as bcl-2 causes cell proliferation. In the abscence of these factors, c-myc expression causes cell death. c-myc gene gives rise to at least two nuclear phosphoproteins of 64kDa and 67kDa, the unphosphorylated form is 49kDa.

Immunogen

Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant full-length human c-Myc protein and mouse myeloma cells.

Formulation

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight

48.8

Database Links:

SwissProtP09416Rat
SwissProtP01108Mouse
SwissProtP01106Human

References

1) K. Alitala et. al. (1983) Proc. Natl. Acad. Sci., 80: 1707-1711

2)H. Person et.al. (1984) Science 225 687-693