Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

Calreticulin

  • Product Code: Z100P
  • Size: 250 µg
  • Price (USD): $244

Cat #

Z100P		 Quantity:      

Data Sheet

Product Name

Calreticulin

Host/Source

Sheep

Isotype

IgG

Product Type

Polyclonal Antibody

Reactivity

Human, Mouse, Rat, Dog

Applications

Western Blot, Immunoprecipitation, Immunohistochemistry

Purification

Ammonium Sulfate Precipitation

Size

250 µg

Price (USD)

$244

Background

Calreticulin, a Ca2+ chaperone, is an abundant highly conserved calcium binding protein found in the lumen of the endoplasmic reticulum of eukaryotic cells. This lumen protein can be used to measure the intactness of membrane preparations. It is used as a marker for subcellular fractionation of cells.

Immunogen

Recombinant protein derived from the carboxy terminus of the calreticulin protein fused to KLH.

Positive Control

MDCK cells; MCF-7 cells. Suitable for use against recombinant proteins conjugated to OVA, GST, His tags and other.

Formulation

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight

60

Product Image

Image Legend

Western blot using antibody at 1:5000 dilution on indicated samples. Immunofluorescence of MCF-7 cells stained with antibody at 1:50 dilution.

Database Links:

SwissProtP28490Canine
SwissProtP18418Rat
SwissProtP14211Mouse
SwissProtQ6IAT4Human

References

1. Kageyama, S., et al. 'Urinary calreticulin in the diagnosis of bladder urothelial carcinoma.' Int. J. Urol. 2009, 16, 481-486 2. Silerova, M., et al. 'Characterization, molecular cloning and localization of calreticulin in Eisenia fetida earthworms.' Gene 2007, 397, 169-177 3. Souto-Padron, T., et al. 'Immunocytochemical localisation of calreticulin in Trypanosoma cruzi.' Histochem. Cell Biol. 2004, 122, 563-569