Exalpha Biologicals, Inc.

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Exalpha Biologicals, Inc. is now a US distributor for Nordic-Mubio products

Nordic-MUbio develops and manufactures high quality antibody reagents for use in R&D. All our products are manufactured according to strict ISO 9001 quality guidelines, and our focus is on developing antibodies targetting Cell Adhesion, Nuclear and Cytoskeletal Proteins.

Nordic-MUbio is one of the leading antibody companies developing antibodies for zebrafish research – we currently have over 50 antibodies validated for immunofluorescence in zebrafish.

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Latest References

Akazawa, Y., et al. "Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis" PLoS ONE 8(12): e82322

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Homa, N.J., et al. "Epstein-Barr Virus Induces Global Changes in Cellular mRNA Isoform Usage That Are Important for the Maintenance of Latency" J. Virol., 2013, 87, 12291-12301

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Exalpha Biologicals, Inc.

BCRP (ATP-binding cassette sub-family G member 2)

  • Product Code: X2731P
  • Size: 100 µg
  • Availability: In Stock In Stock
  • Price (USD): $355

Cat #

X2731P		 Quantity:      

Data Sheet

Product Name

BCRP (ATP-binding cassette sub-family G member 2)


Breast cancer resistance protein; CDw338; Mitoxantrane resistance-associated protein; Placenta-specific ATP-binding cassette transporter





Product Type

Antigen Immunoaffinity Purified Polyclonal




Immunohistochemistry (paraffin-embedded)


Antigen Immunoaffinity Purification


100 µg

Price (USD)



BCRP acts as a xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.


Synthetic peptide derived from human BCRP protein

Positive Control

Highly expressed in placenta


Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight


Product Image

Image Legend

Immunohistochemical staining of normal human testis tissue using BCRP antibody (Cat. No. X2731P) at 10 µg/ml and detected using anti-Rabbit HRP secondary antibody and visualized using DAB substrate and hematoxylin counterstain.

Database Links:



1. Zhou, W., et al. 'The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype.' Nat. Med. 2001, 7, 1028-1034.

2. Itoda, M., et al. ''Eight novel single nucleotide polymorphisms in ABCG2/BCRP in Japanese cancer patients administered irinotacan.' Drug Metab. Pharmacokinet. 2003, 18, 212-217.

3. Zamber, C.P., et al. 'Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine.' Pharmacogenetics 2003, 13, 19-28.