Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

ADAM DEC1

  • Product Code: X2416P
  • Size: 100 µg
  • Price (USD): $244

Cat #

X2416P		 Quantity:      

Data Sheet

Product Name

ADAM DEC1

Synonyms

A disintegrin and metalloproteinase domain-like protein decysin 1,ADAM-like protein decysin 1

Host/Source

Rabbit

Isotype

IgG

Product Type

Polyclonal Antibody

Reactivity

Human

Applications

Western Blot, ELISA

Purification

Ammonium Sulfate Precipitation

Size

100 µg

Price (USD)

$244

Background

ADAMDEC1 is expressed in the immune system, by dendritic cells and macrophages. It may play an important role in the control of the immune response and during pregnancy.1 Due to the partial lack of a disintegrin domain and the total lack of a cysteine-rich domain, this protein has been placed in a novel subclass of the ADAM gene family2.

Immunogen

Synthetic peptide derived from the human ADAMDEC1 protein.

Positive Control

Expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. Predominantly expressed in dendritic cells (DC) of the germinal center. Weakly expressed in monocyte and highly expressed in macrophage. Absent in immature DC.

Formulation

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight

52.7 kDa

Product Image

Image Legend

Staining on paraffin embedded normal human tonsil sections. Primary Ab (IgG cut or immunoaffinity purified) at 10 µg/ml. Antigen retrieval used: 10 mM Na Citrate pH 6.0, 10 minutes pressure cooker method., developed with anti rabbit HRP and DAP substrate. Counterstained with methyl blue.

Database Links:

SwissProtO15204Human

References

1. UniProtKB/Swiss-Prot Acession # O15204 2. Bates, E.E. et. atl., The ADAMDEC1 (decysin) gene structure: evolution by duplication in a metalloprtease gene cluster on chromosome 8p12. Immunogenetics. 2002 May;54(2):96-105. Epub 2002 Mar 16,