Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

APM2 (CT)

  • Product Code: X2385P
  • Size: 100 µg
  • Price (USD): $355

Cat #

X2385P		 Quantity:      

Data Sheet

Product Name

APM2 (CT)

Synonyms

Adipose most abundant gene transcript 2 protein, apM-2, APM2, C10orf116

Host/Source

Rabbit

Isotype

IgG

Product Type

Antigen Immunoaffinity Purified Polyclonal

Reactivity

Human

Applications

Western Blot

Purification

Antigen Immunoaffiinity Purification

Size

100 µg

Price (USD)

$355

Background

APM2 is an ~8kDa protein which until recently was found only in the EST data base but never as an expressed protein. APM2 has since been shown to be associated with cisplatin resistance in cell lines. APM2 is not found in cisplatin sensitive cell lines. These data implicate APM2 in the development of cisplatin resistance in tumor cells.

Immunogen

Synthetic peptide derived from human APM2 protein

Positive Control

Adipose tissue, cornea and liver.

Formulation

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight

7855 Da

Product Image

Image Legend

Immunohistochemical staining of normal human liver tissue using APM2 antibody (Cat. No. X2385P) at 15 µg/ml.

Database Links:

SwissProtQ15847Human

References

1. Scott, B.J., et al. APM2 is a novel mediator of cisplatin resistance in a variety of cancer cell types regardless of p53 or MMR status. Int. J. Cancer 2009, 125, 1193-1204