Exalpha Biologicals, Inc.

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Exalpha Biologicals, Inc.

Degenerative Spermatocyte Homolog 1 (DEGS1)

  • Product Code: X2383P
  • Size: 100 µg
  • Price (USD): $249

Cat #

X2383P		 Quantity:      

Data Sheet

Product Name

Degenerative Spermatocyte Homolog 1 (DEGS1)

Synonyms

Migration-inducing gene 15 protein, MLD, dihydroceramide desaturase, sphingolipid delta 4 desaturase, DES1, MGC5079, DEGS

Host/Source

Rabbit

Isotype

IgG

Product Type

Antigen Immunoaffinity Purified Polyclonal

Reactivity

Human, Rat, Mouse

Applications

Western Blot

Purification

Antigen Immunoaffiinity Purification

Size

100 µg

Price (USD)

$249

Background

The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.

Immunogen

Synthetic peptide derived from the human DEGS1 protein

Positive Control

Placenta, normal human brain

Formulation

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight

37866

Product Image

Image Legend

Immunohistochemical staining of normal human brain tissue using DEGS1 antibody (Cat. No. X2383P) at 15 µg/ml.

Database Links:

SwissProtO09005Mouse
SwissProtQ5XIF5Rat
SwissProtO15121Human

References

1. Cadena, D.L., et al. 'The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis.; Biochemistry 36:6960-6967(1997). 2. Ternes, P., et al. 'Identification and characterization of a sphingolipid delta 4-desaturase family.; J. Biol. Chem. 277:25512-25518(2002).