Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

Beta-site APP-Cleaving Enzyme 1 (BACE1)

  • Product Code: X2230P
  • Size: 50 µg
  • Price (USD): $464

Cat #

X2230P		 Quantity:      

Data Sheet

Product Name

Beta-site APP-Cleaving Enzyme 1 (BACE1)

Synonyms

ASP2, BACE, BACE1, EC 3.4.23.46, FLJ90568, HSPC104, KIAA1149, MEMAPSIN-2

Host/Source

Rabbit

Isotype

IgG

Product Type

Antigen Immunoaffinity Purified Polyclonal

Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Purification

Immunoaffinity Purification

Size

50 µg

Price (USD)

$464

Background

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

Immunogen

internal domain of human

Formulation

Phosphate buffered saline containing 0.1% sodium azide

Customer Storage

Product should be stored at -70ºC. Aliquot to avoid freeze/thaw cycles

Product Image

Image Legend

BACE1 staining of formalin fixed paraffin embedded pancreas tissue at a dilution of 2.5 µg/ml. Antigen retrieval using a citrate buffer and steam/heat was utilized.

Database Links:

SwissProtP56817Human