Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

Brain-Specific Angiogenesis Inhibitor 1 (BAI1)

  • Product Code: X2143P
  • Size: 50 µg
  • Price (USD): $464

Cat #

X2143P		 Quantity:      

Data Sheet

Product Name

Brain-Specific Angiogenesis Inhibitor 1 (BAI1)

Synonyms

BAI1

Host/Source

Rabbit

Isotype

IgG

Product Type

Antigen Immunoaffinity Purified Polyclonal

Reactivity

Human

Applications

Immunohistochemistry

Purification

Immunoaffinity Purification

Size

50 µg

Price (USD)

$464

Background

BAI1 is an Orphan-B GPCR with an unknown ligand. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis, and a growth suppressor of glioblastoma. Along with BAI1, there are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3, which have similar tissue specificities and structures. However, only BAI1 is transcriptionally regulated by p53. Loss of BAI1 expression has been implicated in glioblastoma.

Immunogen

N-terminal domain of human

Positive Control

Human brain tissue

Formulation

Phosphate buffered saline containing 0.1% sodium azide

Customer Storage

Product should be stored at -70°C. Aliquot to avoid freeze/thaw cycles

Product Image

Image Legend

BAI1 staining of formallin fixed paraffin embedded human brain tissue at a dilution of 20 µg/ml. Antigen retrieval using a citrate buffer and steam/heat was utilized.

Database Links:

SwissProtO14514Human

References

1. Mori, K., et al. 'Brain-specific angiogenesis inhibitor 1 (BAI1) is expressed in human cerebral neuronal cells.' Neurosci. Res. 2002, 43, 69-74

2. Hatanaka, H., et al. 'Vascularization is decreased in pulmonary adenocarcinoma expressing brain-specific angiogenesis inhibitor 1 (BAI1).' Int. J. Mol. Med. 2000, 5, 181-183.