Exalpha Biologicals, Inc.

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Exalpha Biologicals, Inc.

5-HT5A Receptor (HTR5A)

  • Product Code: X2142P
  • Size: 50 µg
  • Price (USD): $464

Cat #

X2142P		 Quantity:      

Data Sheet

Product Name

5-HT5A Receptor (HTR5A)

Synonyms

5-HT-5A, 5-HT5A, HTR5A, MGC138226

Host/Source

Rabbit

Isotype

IgG

Product Type

Antigen Immunoaffinity Purified Polyclonal

Reactivity

Human

Applications

Immunohistochemistry

Purification

Immunoaffinity Purification

Size

50 µg

Price (USD)

$464

Background

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.

Immunogen

3rd cytoplasmic domain of human

Positive Control

Human brain.

Formulation

Phosphate buffered saline containing 0.1% sodium azide

Customer Storage

Product should be stored at -70ºC. Aliquot to avoid freeze/thaw cycles

Product Image

Image Legend

HTR5A staining of formalin fixed paraffin embedded human brain (cerebellum) tissue at a dilution of 10 µg/ml. Antigen retrieval using a citrate buffer and steam/heat was utilized.

Database Links:

SwissProtP47898Human

References

1. Doly, S., et al. '5-HT5A receptor localization in the rat spinal cord suggests a role in nociception and control of pelvic floor musculature.' J. Comp. Neurol. 2004, 30, 316-329 2. Wang, Z.Y., et al. '5-HT5a receptors in the carotid body chemoreception pathway of rat.' Neurosci. Lett. 2000, 278, 9-12 3. Garcia-Alcocer, G., et al. 'Serotonin receptor 5-HT5A in rat hippocampus decrease by leptin treatment.' Neurosci. Lett. 2010, 486, 171-173. 4. Yosifova, A., et al. Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. J. Affect Disord 2009, 117, 87-97 5. Schanen, N.C., et al. Assignment of the 5-hydroxytryptamine (serotonin) receptor 5A gene (HTR5A) to human chromosome band 7q36.1. Cytogenet. Cell. Genet. 1996, 72, 187-188