Exalpha Biologicals, Inc.

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Exalpha Biologicals, Inc. is now a US distributor for Nordic-Mubio products

Nordic-MUbio develops and manufactures high quality antibody reagents for use in R&D. All our products are manufactured according to strict ISO 9001 quality guidelines, and our focus is on developing antibodies targetting Cell Adhesion, Nuclear and Cytoskeletal Proteins.

Nordic-MUbio is one of the leading antibody companies developing antibodies for zebrafish research – we currently have over 50 antibodies validated for immunofluorescence in zebrafish.

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Akazawa, Y., et al. "Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis" PLoS ONE 8(12): e82322

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Homa, N.J., et al. "Epstein-Barr Virus Induces Global Changes in Cellular mRNA Isoform Usage That Are Important for the Maintenance of Latency" J. Virol., 2013, 87, 12291-12301

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Exalpha Biologicals, Inc.

5-HT7 Receptor (HTR7)

  • Product Code: X2141P
  • Size: 50 µg
  • Availability: In Stock In Stock
  • Price (USD): $464

Cat #

X2141P		 Quantity:      

Data Sheet

Product Name

5-HT7 Receptor (HTR7)

Synonyms

5-HT-7, 5-HT7, 5HT7, HTR7

Host/Source

Rabbit

Isotype

IgG

Product Type

Antigen Immunoaffinity Purified Polyclonal

Reactivity

Human

Applications

Immunohistochemistry

Purification

Immunoaffinity Purification

Size

50 µg

Price (USD)

$464

Background

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

Immunogen

N-terminal domain of human

Positive Control

Human brain

Formulation

Phosphate buffered saline containing 0.1% sodium azide

Customer Storage

Product should be stored at -70°C. Aliquot to avoid freeze/thaw cycles

Product Image

Image Legend

HTR7 staining of formallin fixed paraffin embedded human brain (cortex) tissue at a dilution of 10 µg/ml. Antigen retrieval using a citrate buffer and steam/heat was utilized.

Database Links:

SwissProtP34969Human

References

1. Grueb, M., et al. 'Serotonin (5-HT7) Receptor-Stimulated Activation of cAMP-PKA Pathway in Bovine Corneal Epithelial and Endothelial Cells.' Ophthalmic. Res. 2012, 48, 22-27.

2. Tonini, M., et al. '5-HT7 receptors modulate peristalsis and accommodation in the guinea pig ileum.' Gastroenterology 2005, 129, 1557-1566.

3. Russo, A., et al. '?In vitro? postnatal expression of 5-HT7 receptors in the rat hypothalamus: an immunohistochemical analysis.' Brain Res. Dev. Brain Res. 2005, 154, 211-216.

4. Meuser, T., et al. '5-HT7 receptors are involved in mediating 5-HT-induced activation of rat primary afferent neurons.' Life Sci. 2002, 71, 2279-2289.