Antibodies recognising M13 filamentous phage coat proteins are instrumental in the selection and detection of phages expressing specific antibody fragments or peptide sequences at their surface. The monoclonal antibodies manufactured and supplied by Exalpha react with either the pIII (g3p) or pVIII (g8p) proteins of M13 filamentous bacteriophage. All antibodies are available in a purified format. The antibodies are fully validated and are suitable for a wide range of techniques including:
For more information, click here for our M13 Bacteriophage information page.
Two more of our excellent products have been published by PubMed:
MMP2; MMP-2; CLG4; CLG4A; Matrix metallopeptidase 2; 72 kDa Type IV collagenase precursor; 72 kDa gelatinase, Gelatinase A
ELISA, Western Blot, Immunohistochemistry
Protein A/G Chromatography
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves Collagen Types IV, V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminus of the human MMP2 protein and mouse myeloma Ag8563 cells.
Oesophageal and gastric tissues. Expression higher cancerous tissue versus normal tissues.
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles