Exalpha Biologicals, Inc.

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Exalpha Biologicals, Inc. is now a US distributor for Nordic-Mubio products

Nordic-MUbio develops and manufactures high quality antibody reagents for use in R&D. All our products are manufactured according to strict ISO 9001 quality guidelines, and our focus is on developing antibodies targetting Cell Adhesion, Nuclear and Cytoskeletal Proteins.

Nordic-MUbio is one of the leading antibody companies developing antibodies for zebrafish research – we currently have over 50 antibodies validated for immunofluorescence in zebrafish.

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Latest References

Akazawa, Y., et al. "Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis" PLoS ONE 8(12): e82322

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Homa, N.J., et al. "Epstein-Barr Virus Induces Global Changes in Cellular mRNA Isoform Usage That Are Important for the Maintenance of Latency" J. Virol., 2013, 87, 12291-12301

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Exalpha Biologicals, Inc.

alpha T-Catenin

  • Product Code: X1726M
  • Size: 100 µg
  • Availability: In Stock In Stock
  • Price (USD): $355

Cat #

X1726M		 Quantity:      

Data Sheet

Product Name

alpha T- Catenin


Cadherin-associated protein







Product Type

Monoclonal Antibody




Immunofluorescence, Immunocytochemistry, Immunoprecipitation, Western Blot


Protein A/G Chromatography


100 µg

Price (USD)



Catenins are proteins that connect cadherin/ -catenin cell adhesion complexes to the actin cytoskeleton. Although originally discovered in testis, T-catenin is expressed in other tissues, the highest levels being observed in heart. Immunohistochemical analysis showed human Tcatenin localization at intercalated discs of cardiomyocytes and in peritubular myoid cells of testis. It is proven that T-catenin can functionally restore cell-cell adhesion in colon cancer cells lacking -catenins. This indicates that this protein is involved in the formation of specific cell-cell contacts in specific types of muscle cells. The encoded protein has about the same predicted size (100 kDa) as other -catenins to which it shows an overall amino acid identity of 57%. In cells transfected with T-catenin cDNA, interaction with -catenin was demonstrated by coimmunoprecipitation. This antibody is specific for T-catenin and does not cross react with E-catenin or N-catenin by Western blot.


Hybridoma produced by the fusion of splenocytes from C57BI/6 mice immunized with a synthetic peptide derived from the human T-catenin protein and SP2/0-Ag14 mouse myeloma cells.


Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight

~100 kDa

Database Links:



1. Janssens, B., et al. 'alphaTcatenin: a novel tissue-specific beta-cateninbinding protein mediating strong cell-cell adhesion', J. Cell. Sci. 2001, 114, 3177-88.