Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

Adiponectin Receptor 2

  • Product Code: X1699P
  • Size: 100 µg
  • Price (USD): $355

Cat #

X1699P		 Quantity:      

Data Sheet

Product Name

Adiponectin Receptor 2

Synonyms

Adiponectin receptor protein 2, Progestin and adipoQ receptor family member II, ADIPOR2, PAQR2

Host/Source

Rabbit

Product Type

Polyclonal Antibody

Reactivity

Human

Applications

Western Blot, ELISA

Purification

Ammonium Sulfate Precipitation

Size

100 µg

Price (USD)

$355

Background

ADR2 functions as a receptor for globular and full-length adiponectin (APM1), which is an essential hormone secreted by adipocytes that acts as an antidiabetic. ADR2 is also probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. ADR2 mediates an increase in AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin and has some intermediate-affinity receptor activity for both globular and full-length adiponectin. ADR2 may form homo and heteromultimers.

Immunogen

Synthetic peptide near the C terminus of human adiponectin receptor 2 protein.

Positive Control

Colon, Hippocampus, and Trachea

Formulation

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight

43884

Database Links:

SwissProtQ86V24Human

References

1. Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., , Marra M.A.; Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.; Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). 2. Yamauchi T., Kamon J., Ito Y., Tsuchida A., Yokomizo T., Kita S., Sugiyama T., Miyagishi M., Hara K., Tsunoda M., Murakami K., Ohteki T., Uchida S., Takekawa S., Waki H., Tsuno N.H., Shibata Y., Terauchi Y., Froguel P., , Kadowaki T.; Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.; Nature 423:762-769(2003).