Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery

Product Highlight

Mouse anti-M13 phage coat protein g8p

Antibodies recognising M13 filamentous phage coat proteins are instrumental in the selection and detection of phages expressing specific antibody fragments or peptide sequences at their surface. The monoclonal antibodies manufactured and supplied by Exalpha react with either the pIII (g3p) or pVIII (g8p) proteins of M13 filamentous bacteriophage. All antibodies are available in a purified format. The antibodies are fully validated and are suitable for a wide range of techniques including:

  • Flow Cytometry
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
For more information, click here for our M13 Bacteriophage information page.


Two more of our excellent products have been published by PubMed:

Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis
Borazanci, E., et al., J. Gastrointest. Oncol., 8, 164-172 (2017)
Using Exalpha SPARC Antibody (Cat. No. X1867P)

Molecular mechanism underlying the pharmacological interactions of the protein kinase C-β inhibitor enzastaurin and erlotinib in non-small cell lung cancer cells
Steen, N.V., et al., Am. J. Cancer Res., 7, 816-830 (2017)
Using Exalpha's FITC labeled anti PY20 Antibody (Cat. No. X1017)

Exalpha Biologicals, Inc.

PTP-PEST (2-300)/PTPN12 N Terminal GST Tag

  • Product Code: X1664E
  • Size: 20 µg
  • Price (USD): $361

Cat #

X1664E		 Quantity:      

Data Sheet

Product Name

PTP-PEST (2-300)/PTPN12 N Terminal GST Tag


Protein-tyrosine phosphatase G1, PTPG1



Product Type

Active Enzyme




Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.


20 µg

Price (USD)



PEST also known as Tyrosine-protein phosphatase, non-receptor type 12 (PTPN12), Protein-tyrosine phosphatase G1 or PTPG1 is a protein-tyrosine phosphatase (PTP) involved in regulating the Wiskott-Aldrich syndrome protein (WASp). WASp is tyrosine dephosphorylated by (PTP)-PEST via proline, serine, threonine phosphatase interacting protein (PSTPIP)1 binding. PTP-PEST combined with PSTPIP1 inhibits WASp-driven actin polymerization and synapse formation. PTP-PEST plays a central role in regulating WASp and is absolutely required for WASp contributions to T cell activation.


Recombinant enyzme produced in E. coli


Provided in 25 mM Tris-HCl, 75 mM NaCl, pH 8.0, 0.05% Tween, 5 mM DTT and 50% glycerol

Customer Storage

Enzyme should be stored at -20°C. Enzyme should be kept on ice when dispensing

Target Molecular Weight


Database Links:



[1] Takekawa M., Itoh F., Hinoda Y., Arimura Y., Toyota M., Sekiya M., Adachi M., Imai K., Yachi A.; Cloning and characterization of a human cDNA encoding a novel putative cytoplasmic protein-tyrosine-phosphatase.; Biochem. Biophys. Res. Commun. 189:1223-1230(1992).

[2] Yang Q., Co D., Sommercorn J., Tonks N.K.;
Cloning and expression of PTP-PEST. A novel, human, nontransmembrane protein tyrosine phosphatase.; J. Biol. Chem. 268:6622-6628(1993).

[3] Yang Q., Co D., Sommercorn J., Tonks N.K.; pest
J. Biol. Chem. 268:17650-17650(1993).

[4] Schmidt-Arras DE, Bohmer A, Markova B, Choudhary C, Serve H, Bohmer FD. Tyrosine phosphorylation regulates maturation of receptor tyrosine kinases.
Mol Cell Biol. 2005 May;25(9):3690-703.

[5] Wisniewska M, Bossenmaier B, Georges G, Hesse F, Dangl M, Kunkele KP, Ioannidis I, Huber R, Engh RA. The 1.1 A resolution crystal structure of the p130cas SH3 domain and ramifications for ligand selectivity. J Mol Biol. 2005 Apr 15;347(5):1005-14.

[6] Badour K, Zhang J, Shi F, Leng Y, Collins M, Siminovitch KA. Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation.
J Exp Med. 2004 Jan 5;199(1):99-112.