Sphingosine 1-Phosphate Phosphatase 2
- Product Code: X1637P
- Size: 100 µg
- Price (USD): $249
Cat #
Data Sheet
Product Name
Sphingosine 1-Phosphate Phosphatase 2
Synonyms
Sphingosine 1-Phosphate Phosphohydrolase
Host/Source
Rabbit
Isotype
Not applicable
Product Type
Antigen Immunoaffinity Purified Polyclonal
Reactivity
Human
Applications
Western Blot
Purification
Antigen Immunoaffiinity Purification
Size
100 µg
Price (USD)
$249
Background
Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/G-protein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. SPPase2 is localized to the endoplasmic reticulum. The enzymatic activity and localization of SPPase2 are similar to SPPase1. The tissue expression of SPPase2 was different from that of SPPase1. SPPase2 is an important member of the SPPase family which play a role in attenuating intracellular S1P signaling.
Immunogen
Synthetic peptide derived from the sphingosine 1-phosphate phosphatase 2 protein.
Positive Control
Human brain lysate (Cat. No. X1633C)
Formulation
Provided as whole antiserum
Customer Storage
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
Database Links:
| SwissProt | Q8IWX5 | Human |
