Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

Protein Kinase C-Holoenzyme

  • Product Code: X1606RP
  • Size: 1000 Units
  • Price (USD): $200

Cat #

X1606RP		 Quantity:      

Product Name

Protein Kinase C-Holoenzyme

Host/Source

Rat Brain

Product Type

Active Enzyme

Applications

Enzyme activity assay standard

Size

1000 Units

Price (USD)

$200

Background

Protein kinase C (PKC) is a multifunctional protein kinase that plays a critical regulatory role in a wide variety of cellular signaling processes. It is an ubiquitous calcium and phospholipid-dependent protein kinase. At least 10 PKC isoforms are reported to exist which are classified as conventional (?, ?, ?), novel (?, ?, ?, ?, ?), and atypical (?, ?) isoforms (Ohno and Nishizuka, 2002). PKC is one of the three major protein kinases (including CaM Kinase II and PKA) that mediate cellular responses to second messengers. PKC regulates a number of cellular functions including neurotransmitter synthesis and release, gene expression, ion channel function and synaptic plasticity (Lu et al., 1999; Grosshans et al., 2002; Nishizuka, 1995).