Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

ALK/p80

  • Product Code: X1320M
  • Size: 100 µg
  • Price (USD): $234

Cat #

X1320M		 Quantity:      

Product Name

ALK/p80

Host/Source

Mouse

Clone

ALK01

Isotype

IgG1

Product Type

Monoclonal Antibody

Size

100 µg

Price (USD)

$234

Background

Recognizes a human p80 protein, identified as a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in a third of large cell lymphomas. This antibody may be used to detect p80 in these lymphomas. In addition, this antibody may also be used to detect a recently described subtype of large B cell lymphoma, which expresses the full-length ALK protein.

Formulation

Tissue culture supernatant with 15 mM sodium azide.

Customer Storage

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

References

1. Pittaluga S, et al. The monoclonal antibody ALK1 identifies a distinct morphological subtype of anaplastic large cell lymphoma associated with 2p23/ALK rearrangements. American Journal of Pathology. 151(2):343-351 (1997). 2. Pulford K, et al. Detedtion of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1. Blood. 89(4): 1394-1404 (1997) 3. Downing J R, et al. Molecular detection of the (2;5) translocation of non-Hodgkin’s lymphoma by reverse transcriptase-polymerase chain reaction. Bloob. 85(12): 3416-3422 (1995).