Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

NAP-2

  • Product Code: X1251C
  • Size: 20 µg
  • Price (USD): $450

Cat #

X1251C		 Quantity:      

Product Name

NAP-2

Synonyms

Neutrophil Activating Peptide 2

Product Type

Synthetic Protein

Applications

Activity Assay

Size

20 µg

Price (USD)

$450

Background

NAP-2 (Neutrophil Activating Peptide 2) is a member of the CXC chemokine family. It is similar to other ELR domain containing chemokines to CXC receptors such as interleukin-8 and GRO proteins. NAP-2 binds to CXCR-2 and chemoattracts and activates neutrophils. NAP-2 is a proteolytically processed carboxyl-terminal fragment of platelet basic protein (PBP) and is found in the ?-granules of human platelets.

Formulation

Lyophilized

Customer Storage

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

References

1. Wenger R.H., et al., 'Cloning of cDNA coding for connective tissue activating peptide III from a human platelet-derived lambda gt11 expression library.' Blood 1989: 73, 1498-1503 2. Iida N. et al., 'Leukocyte-derived growth factor links the PDGF and CXC chemokine families of peptides.' FASEB J. 1996: 10, 1336-1345 3. Schröder, J.M. et al., 'Purification and partial biochemical characterization of a human monocyte-derived, neutrophil-activating peptide that lacks interleukin 1 activity.' J. Immunol. 1987: 139, 3474-3483 4. Walz, A., et al. 'Formation and biologicals properties of neurtrophil activating peptide 2 (NAP-2).' Adv. Exp. Med. Biol. 1991: 305, 39-46