Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

Mip1a

  • Product Code: X1244C
  • Size: 20 µg
  • Price (USD): $375

Cat #

X1244C		 Quantity:      

Product Name

Mip1a

Synonyms

Macrophage Inflammatory Protein 1?; CCL3

Product Type

Synthetic Protein

Applications

Activity Assay

Size

20 µg

Price (USD)

$375

Background

MIP-1? (Macrophage Inflammatory Protein 1? or CCL3) is a monocyte chemoattractant which has chemoattractant and adhesive effects on lymphocytes, preferentially attracting CD8+ cells. MIP-1? has also been shown to attract B cells and also eosinophils. It has also been identified as a stem cell inhibitory factor which can inhibit the proliferation of hematopoietic stem cells in vitro and in vivo. Receptors for MIP-1? are CCR1 and CCR5.

Formulation

Lyophilized

Customer Storage

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

References

1. Menten, P. et al. 'Macrophage inflammatory protein-1.' Cytokine Growth Factor Rev. 2002: 13, 455-481 2. Owen-Lynch, P.J., et al. 'The growth inhibitory role and potential clinical value of macrophage inflammatory protein 1 alpha in myeloid leukaemias.' Leuk. Lymphoma 1998: 30, 41-53 3. Broxmeyer, H.E., et al. 'Advances in undestanding of biological effects of interleukin-11, leukemia inhibitory factor, and macrophage inflammatory protein 1 alpha.' Curr. Opin. Hematol. 1994: 1, 197-202.