- Product Code: X1051
- Size: 20 Tests
- Price (USD): $682
Flow Cytometry Kits
CYCLOSCOPE B-NHL, is a kit used for the flow cytometric analysis of DNA cell contents in B- cell non-Hodgkin's Lymphoma (B-NHL) and B-lineage chronic lymphocytic leukemias (B-CLL). This kit is mainly focused for DNA studies of B-cells from bone marrow or peripheral blood samples of these patients.In recent years, DNA flow cytometry studies have extended from basic research to clinical laboratories. Thus, flow cytometry analysis of the distribution of the cell nuclei DNA contents is being widely used to estimate the cell cycle distribution and the existence of DNA aneuploidy of either normal and tumour cell populations. Cycloscope kits are based on the combination of DNA cell measurements together with the analysis of tumoral cell antigen expression. This double staining method allows the identification of the neoplastic cells present in the sample in order to performe a DNA analysis separately from that of normal hemopoietic cells, as it is recommended by different consensus reports on DNA analysis by flow cytometry in neoplastic hematopathology.Previous studies have demonstrated that the percentage of tumor B-cells in S-phase have a clear role as an independent prognostic factor either in non-Hodgkin`s lymphoma or in chronic lymphocytic leukemia. On the other hand, it has been shown that DNA-ploidy correlates well with histopathologic grade in non-Hodgkin's lymphoma patients.
Product should be stored at 4-8ºC. DO NOT FREEZE