Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery

Product Highlight

Mouse anti-M13 phage coat protein g8p

Antibodies recognising M13 filamentous phage coat proteins are instrumental in the selection and detection of phages expressing specific antibody fragments or peptide sequences at their surface. The monoclonal antibodies manufactured and supplied by Exalpha react with either the pIII (g3p) or pVIII (g8p) proteins of M13 filamentous bacteriophage. All antibodies are available in a purified format. The antibodies are fully validated and are suitable for a wide range of techniques including:

  • ELISA
  • Flow Cytometry
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
For more information, click here for our M13 Bacteriophage information page.

News

Two more of our excellent products have been published by PubMed:

Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis
Borazanci, E., et al., J. Gastrointest. Oncol., 8, 164-172 (2017)
Using Exalpha SPARC Antibody (Cat. No. X1867P)

Molecular mechanism underlying the pharmacological interactions of the protein kinase C-β inhibitor enzastaurin and erlotinib in non-small cell lung cancer cells
Steen, N.V., et al., Am. J. Cancer Res., 7, 816-830 (2017)
Using Exalpha's FITC labeled anti PY20 Antibody (Cat. No. X1017)

Exalpha Biologicals, Inc.

ADAR2 (Adenosine Deaminase Acting on RNA 2)

  • Product Code: U115P
  • Size: 50 µg
  • Availability: In Stock In Stock
  • Price (USD): $244

Cat #

U115P		 Quantity:      

Data Sheet

Product Name

ADAR2 (Adenosine Deaminase Acting on RNA 2)

Synonyms

RED-1, RED1; ADAR2, DRADA2 dsRNA adenosine deaminase, RNA-editing deaminase 1, RNA-editing enzyme 1

Host/Source

Sheep

Isotype

IgG

Product Type

Antigen Immunoaffinity Purified Polyclonal

Reactivity

Rat

Applications

Western Blot

Purification

Antigen Immunoaffiinity Purification

Size

50 µg

Price (USD)

$244

Background

RED 1 also called ADAR2 is involved in the editing of the messenger RNAs for glutamate receptor (GluR) subunits by site-selective adenosine deamination. It edits both the GluR-B Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently.

Immunogen

GST fusion protein containing aa 6-66 of the rat RED1 coding sequence

Positive Control

Rat Brain

Formulation

Affinity Purified

Customer Storage

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight

80.7 kDa

Product Image

Image Legend

Immunofluorescence staining of mouse anterior horns of spinal cord at 6 months, 15 months and 26 months of age. Antibody used at 1:100 dilution and visualized using donkey anti-sheep conjugated to Alexa 555 dye (red color). The blue color is a fluorescent nuclear probe, TOPRO3. (Image modified from original in citation 1)

Database Links:

SwissProtP51400Rat

Product Specific References


This product has been used in:

1. Hideyama, T., et al. ‘Co-Occurrence of TDP-43 Mislocalization with Reduced Activity of an RNA Editing Enzyme, ADAR2, in Aged Mouse Motor Neurons’ PLoS One, 7, e43469, 2012
2. Yamashita, T., et al. ‘Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons.’ EMBO Mol. Med., 2013, 5, 1710-1719