Exalpha Biologicals, Inc.

Latest News

Exalpha Biologicals, Inc. is now a US distributor for Nordic-Mubio products

Nordic-MUbio develops and manufactures high quality antibody reagents for use in R&D. All our products are manufactured according to strict ISO 9001 quality guidelines, and our focus is on developing antibodies targetting Cell Adhesion, Nuclear and Cytoskeletal Proteins.

Nordic-MUbio is one of the leading antibody companies developing antibodies for zebrafish research – we currently have over 50 antibodies validated for immunofluorescence in zebrafish.

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Latest References

Akazawa, Y., et al. "Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis" PLoS ONE 8(12): e82322

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Homa, N.J., et al. "Epstein-Barr Virus Induces Global Changes in Cellular mRNA Isoform Usage That Are Important for the Maintenance of Latency" J. Virol., 2013, 87, 12291-12301

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Exalpha Biologicals, Inc.

Disabled (NT)

  • Product Code: U100P
  • Size: 250 µg
  • Availability: In Stock In Stock
  • Price (USD): $244

Cat #

U100P		 Quantity:      

Data Sheet

Product Name

Disabled (NT)


Disabled homolog 1; DAB1





Product Type

Polyclonal Antibody




Western Blot


Ammonium Sulfate Precipitation


250 µg

Price (USD)



Disruption of the disabled-1 gene (Dab1) results in aberrant migration of neurons during development and disorganization of laminar structures throughout the brain. Dab1 is thought to function as an adaptor molecule in signal transduction processes. It contains a protein-protein interaction (PI) similar to the phosphotyrosine binding domain of the Shc oncoprotein, it is phosphorylated by the Src protein tyrosine kinase, and it binds to SH2 binding domains in a phosphotyrosine dependent manner. Disabled ?1 acts downstream of reelin in a signalling pathway.


Recombinant protein corresponding to amino acids 1-179 of mouse disabled coupled to a GST fusion protein.

Positive Control

293 cells transfected with Dab-1 HA tag


Provided as 0.2mm sterile filtered solution in phosphate buffered saline with 0.08% sodium azide.

Customer Storage

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight


Product Image

Image Legend

Western blot analysis using Disabled-1 (NT) (Cat. No. U100P) (1) and (CT) (Cat. No. U105P) (2) on mouse brain extracts.

Database Links:



1. Howell B.W. et.al (1997). EMBO Journal 1,121-132
2. Homayouni,R. et.al (1999) J. Neuroscience 19(17), 7505-7515

Product Specific References

This product has been used in:

1. Cuchillo-Ibanez, I., et al. ?Beta-Amyloid Impairs Reelin Signaling.? PLoS One, 8, e72297 (2013)