Exalpha Biologicals, Inc.

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Exalpha Biologicals, Inc.

KSHV/HHV8 (minor capsid protein)

  • Product Code: F110P
  • Size: 250 µg
  • Price (USD): $237

Cat #

F110P		 Quantity:      

Product Name

KSHV/HHV8 (minor capsid protein)

Synonyms

HHV8mCP; ORF26

Host/Source

Sheep

Isotype

IgG

Product Type

Polyclonal Antibody

Reactivity

N/A

Applications

Western Blot, Immunoprecipitation

Purification

Ammonium Sulfate Precipitation

Size

250 µg

Price (USD)

$237

Background

Human herpervirus-8 (HHV-8) minor capsid protein is a component of the HHV-8 virus particle. It was the first HHV-8 gene cloned and served as a PCR marker for HHV-8 infection. The mCP is expressed during the lytic phase of the virus life cycle and is an excellent marker for identification of infected cells actively producing virus particles,

Immunogen

Recombinant full-length KSHV minor capsid protein

Formulation

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Target Molecular Weight

32 kda

Product Image

Image Legend

Western blot of BCBL1 cells (Lane 1) and BCBL1 cells cultured in the presence of 20 ng/ml TPA for 48 h (Lane 2) using KSHV minor capsid protein antibody (Cat. No. F110P) at 2 µg/ml and visualized using rabbit anti-sheep antibody conjugated to HRP and ECL.

Database Links:

SwissProtC7E599Human

References

1. Lin, S.F., et al. ‘Identification, expression, and immunogenicity of Kaposi's sarcoma-associated herpesvirus-encoded small viral capsid antigen.’ J. Virol. 71, 3069-3076 (1997) 2. Cannon, M., et al. ‘KSHV G protein-coupled receptor inhibits lytic gene transcription in primary-effusion lymphoma cells via p21-mediated inhibition of Cdk2’ Blood, 107, 277-284 (2005)


Product Specific References


This product has been used in:

1. Baquero-Perez, B., Whitehouse, A. 'Hsp70 Isoforms Are Essential for the Formation of Kaposi's Sarcoma-Associated Herpesvirus Replication and Transcription Compartments.' PLoS Pathog,, 11, e1005274 (2015)