Exalpha Biologicals, Inc.

Accelerating the Pace of Discovery
Exalpha Biologicals, Inc.

CD42a PE

  • Product Code: 42A4
  • Size: 100 Tests
  • Price (USD): $191

Cat #

42A4		 Quantity:      

Data Sheet

Product Name

CD42a PE

Synonyms

CD42a PE

Host/Source

Mouse

Clone

ESS

Isotype

IgG1

Product Type

Single-Color Reagent

Reactivity

Human

Applications

Flow Cytometry

Purification

Protein A/G Chromatography

Size

100 Tests

Price (USD)

$191

Background

Single-chain membrane glycoprotein that forms a non-covalent complex with GPIb. (MW23kDa) Reactivity with resting and activated platelets, weakly on monocytes, megakaryocytes and attachment site for the platelet plasma membrane to the submembrane cytoskeleton. GPIb/IX complex, functions as the receptor for ristocetin-induced binding of von Willebrand factor and as the von Willebrand factor-depend adhesion receptor.

Formulation

Provided as sterile filtered solution in phosphate buffered saline with 0.08% sodium azide and 0.2% carrier protein

Customer Storage

Product should be stored at 4-8ºC. DO NOT FREEZE

Database Links:

SwissProtP14770Human

References

1. Detection of platelet activation with monoclonal antibodies and flow cytometry. Fijnheer R., Modderman P.W., Veldman H., et al. Transfusion 1990:30:20-25 2. Glycoprotein Ib and glycoprotein IX are fully complexed in the intact platelet membrane Du X, Beutler L., Ruan C., Castaldi P.A., and Berndt M.C., Blood 1987:69:1524-1527 3. Structure of the glycoprotein Ib-IX complex from platelet membranes Fox JEB, Aggerbeck L.P., Berndt M.C., J. Biol. Chem. 1988:263:4882-4890 4. Leucocyte Typing IV: White Cell Differentiation Antigens Nieuwenhuis H.K. Report on functional studies. In: Knapp W., Dorken B., Gilks W.R., et al, eds. Oxford: Oxford University Press: 1989:1002-1003.


Product Specific References


This product has been used in:

1. Heilmann, C., et al, 'Staphylococcus aureus Fibronectin-Binding Protein (FnBP)–Mediated Adherence to Platelets, and Aggregation of Platelets Induced by FnBPA but Not by FnBPB' Journal of Infectious Disease 2004, 190, , 321-329