Exalpha Biologicals, Inc.

Product Highlight

FIX&PERM Cell Fixation and Permeabilization Kit

Flow cytometric analyses with monoclonal antibodies were so far mainly restricted to cell surface molecules. Intracellular structures such as cytoplasmic or nuclear enzymes, oncoproteins, cytokines, immunoglobulins etc. were largely excluded from such studies. Also excluded from flow cytometric studies were cytoplasmic localizations of well-established membrane molecules like CD3 and CD22, which, in their cytoplasmic form, are the most reliable lineage markers in undifferentiated leukemia. With the FIX&PERM® Kit flow cytometric analysis of intracellular antigens has become as easy as surface antigen studies. The only prerequisite is the availability of suitable antibody conjugates. Most of the available monoclonal antibody conjugates can be used with the FIX&PERM® Kit, some determinants are sensitive, however, to the fixation step involved. This and the optimal fixation time have to be tested for each reagent.

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Welcome, Peter Rutten

We are pleased to announce that Peter Rutten has now started in his role as Operations Director here at Exalpha Biologicals Inc. Peter has a Master’s of Science degree in Industrial and Organizational Psychology and this has lead him down a very business orientated career path. Peter is looking forward to working with the team at Exalpha. Peters primary focus is the customer experience and he will be working with the Laboratory team, the Quality Control team and the Order Processing team to ensure this focus is achieved. We all wish Peter well in his new role.

Exalpha Biologicals, Inc.

CD56 Prediluted

  • Product Code: 0561P
  • Size: 7 ml
  • Availability: In Stock In Stock
  • Price (USD): $232

Cat #

0561P		 Quantity:      

Data Sheet

Product Name

CD56 Prediluted

Synonyms

CD56, NCAM, Neural Cell Adhesion Molecule

Host/Source

Mouse

Clone

C5.9

Isotype

IgG2b

Product Type

Monoclonal Antibody

Reactivity

Human

Applications

Immunohistochemistry

Purification

Protein A/G Chromatography

Size

7 ml

Price (USD)

$232

Background

CD56, M.W. 150,000, is expressed on approximately 10-25% of human peripheral blood lymphocytes. CD56 (NKH-1) is expressed on human peripheral blood natural killer cells, representing a pan NK-cell antigen. Expressed on non-MHC-restricted cytotoxic T cells. Exalpha?s CD56, clone C5.9 has been recognized as the superior CD56 antibody for Flow Cytometry applications because of it?s specific and intense staining. In fact, our CD56 is bright enough to be used in FITC! Now this antibody is proven to work in formalin fixed paraffin embedded section. Available concentrated, pre-diluted in dropper bottles, or conjugated to several flurochromes for manual use or automated applications.

Immunogen

Derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c F1 mice immunized with KG1a cell line.

Formulation

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Customer Storage

Product should be stored at 4-8°C. DO NOT FREEZE

Target Molecular Weight

94.5 kDa

Database Links:

SwissProtP13591Human

References

1. Muench, Marcus O., et al. Isolation of Definitive Zone and Chromaffin Cells Based upon Expression of CD56 (Neural Cell Adhesion Molecule) in the Human Fetal Adrenal Gland, The Jurnal of ClinicalEndocrinology & Metabolism, 2003, Vol 88(8) Pages 3921-3930,