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Sodium/hydrogen exchanger 1

Catalogue number: X2339B

Product Type Blocking Peptide
Units50 µg
HostRabbit
Species reactivity Human
Application Western Blot

Background
NHE-1 is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. NHE-1 plays an important role in signal transduction. Located in the kidney and intestine.

Synonyms: Sodium/hydrogen exchanger 1; NHE-1; SL9A1; Solute carrier family 9 member 1

Source

Immunogen: Synthetic peptide derived from the human NHE-1 protein

Product

Product Form: Unconjugated

Formulation: Provided as solution in phosphate buffered saline

Concentration: See vial for concentration

Applications
For use with NHE1 polyclonal antibodies (Cat. No. X2315P & X2338P).

Functional Analysis: Western Blotting

Positive Control: Protein expressed in kidney and intestine.

Storage
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: Products are stable for one year from purchase when stored properly

Shipping Conditions: Ship at ambient temperature, freeze upon arrival

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

References
1. Pang, T., et al. 'Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger.; J. Biol. Chem. 277:43771-43777(2002). 2. Slepkov, E.R., et al. 'Proline residues in transmembrane segment IV are critical for activity, expression and targeting of the Na+/H+ exchanger isoform 1.; Biochem. J. 379:31-38(2004). 3. Slepkov, E.R., et al. 'Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger.; J. Biol. Chem. 280:17863-17872(2005).

Protein Reference(s)

Database Name: UniProt

Accession number: P19634

Species Accession: Human


Sodium/hydrogen exchanger 1

$121.00


Brand

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Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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