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Mouse anti Human alpha/beta SNAP

Catalogue number: X1024

Clone16D1
IsotypeIgG2b
Product Type Monoclonal Antibody
Units100 µg
HostMouse
Species reactivity Bovine
Chicken
Human
Rat
Application Western Blot
Western Blotting

Background
38 kDa SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide- sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-toendosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. Alpha-SNAP (or beta-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.

Synonyms: alpha/beta SNAP, mouse anti alpha/beta soluble NSF attachment protein

Source
Mouse monoclonal antibody 16D1 raised after immunisation with recombinant human alpha SNAP.

Immunogen: Recombinant human alpha SNAP

Product
100 µg monoclonal antibody in 20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, pH 7.5

Formulation: 20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, pH 7.5

Concentration: See vial for concentration

Specificity
Human alpha/beta SNAP

Applications
Suggested dilution for Western blotting: 1:5000 (Optimal concentration should be evaluated by serial dilutions.)

Functional Analysis: Western Blotting

Positive Control: Rat brain

Storage
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: Products are stable for one year from purchase when stored properly

Shipping Conditions: Ship at ambient temperature, freeze upon arrival

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Exalpha Biologicals accepts no liability for any inaccuracies or omissions in this information.

Protein Reference(s)

Database Name: UniProt

Accession number: P54920 (Human)

Species Accession: Human


Safety Datasheet(s) for this product:
EA_Glycerol
/wp-content/uploads/SDS/Antibody SDS with glycerolV2.pdf

Mouse anti Human alpha/beta SNAP

$261.00


Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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