Mouse anti Human alpha/beta SNAPCatalogue number: X1024
|Product Type||Monoclonal Antibody|
38 kDa SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide- sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-toendosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. Alpha-SNAP (or beta-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.
Synonyms: alpha/beta SNAP, mouse anti alpha/beta soluble NSF attachment protein
Mouse monoclonal antibody 16D1 raised after immunisation with recombinant human alpha SNAP.
Immunogen: Recombinant human alpha SNAP
100 µg monoclonal antibody in 20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, pH 7.5
Formulation: 20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, pH 7.5
Concentration: See vial for concentration
Human alpha/beta SNAP
Suggested dilution for Western blotting: 1:5000 (Optimal concentration should be evaluated by serial dilutions.)
Functional Analysis: Western Blotting
Positive Control: Rat brain
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
Product Stability: Products are stable for one year from purchase when stored properly
Shipping Conditions: Ship at ambient temperature, freeze upon arrival
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Exalpha Biologicals accepts no liability for any inaccuracies or omissions in this information.
Database Name: UniProt
Accession number: P54920 (Human)
Species Accession: Human
Safety Datasheet(s) for this product:
/wp-content/uploads/SDS/Antibody SDS with glycerolV2.pdf
Mouse anti Human alpha/beta SNAP