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Serine Palmitoyltransferase 1

Catalogue number: X2067B

Long chain base biosynthesis protein 1; LCB-1; LCB1; Serine-palmitoyl-CoA transferase 1; SPT1; SPT 1; SPT-1

Product Type Blocking Peptide
Units50 µg
Species reactivity Human
Application Immunohistochemistry
Western Blot
Product Form

Sphingolipids play essential roles in various cellular events, including proliferation, differentiation, senescence, apoptosis, and inflammatory responses. Serine palmitoyltransferase (SPT) is the initial and rate-limiting enzyme in the de novo sphingolipid biosynthesis, and thus regulates the level of sphingolipids in cells. Immunohistochemical study revealed widespread distribution of the enzyme with most strong expression in brain and digestive tract. Two subunits, SPT1 and SPT2 at a stoichiometry of 1:1, are involved in the enzymatic activity of SPT.

See vial for concentration

Provided as solution in phosphate buffered saline

Functional Analysis
Antibody Function Blocking

For use with serine palmitoyltransferase 1 polyclonal antibodies (Cat. No. X1862P & X2066P).

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Ship Conditions
Ship at ambient temperature, freeze upon arrival

Product Stability
Products are stable for one year from purchase when stored properly

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

Safety Datasheet(s) for this product:

Serine Palmitoyltransferase 1


SKU: X2067B Categories: ,