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Sheep anti Human Rhombotin 2

Catalogue number: N105P

Product Type Polyclonal Antibody
Units250 µg
Species reactivity Human
Application Western Blot

Two homologues of the rhombotin gene have now been isolated. One of these, designated Rhom-2, is located on human chromosome 11 at band 11p13, where a cluster of T-cell leukemia-specific translocations occur; all translocation breakpoints at 11p13 are upstream of the Rhom-2 gene. Human and mouse Rhom-2 are highly conserved and, like rhombotin, encode two tandem cysteine-rich LIM domains. Rhom-2 mRNA is expressed in early mouse development in central nervous system, lung, kidney, liver, and spleen but only very low levels occur in thymus. The Rhom-2 gene is such a common site of chromosomal damage in T-cell tumors. Chromosome bands 11p15 (rhombotin) and 11p13 (Rhom-2) are consistent sites of chromosome translocation in T-cell leukemia, with the 11p15 target more rarely involved.

Synonyms: LIM domain only protein; cysteine-rich protein TTG-2; T-cell translocation protein 2


Immunogen: Full length rhombotin 2 protein


Product Form: Unconjugated

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Purification Method: Ammonium Sulfate Precipitation

Concentration: See vial for concentration

Western Blots at 1-10 ug /ml

Functional Analysis: Western Blotting

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: Antibodies are stable for one year from purchase if stored frozen

Shipping Conditions: Room Temperature

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

Protein Reference(s)

Database Name: UniProt

Accession number: P25791 (Human)

Species Accession: Human

Safety Datasheet(s) for this product:
Sodium Azide

Sheep anti Human Rhombotin 2



Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370