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Monocarboxylate Transport 2

Catalogue number: X2372B

Product Type Blocking Peptide
Units50 µg
Species reactivity Human
Application Western Blot

Functions as a proton-linked monocarboxylate transporter and catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a very high affinity pyruvate transporter. MCT2 is a cell membrane; Multi-pass membrane protein with high expression in testis, moderate to low expression in spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocytes. The normal expression of MCT2 is restricted to low levels of expression in normal tissues, but is widely expressed in cancer cells.

Synonyms: MCT2; Solute carrier family 16 member 7; SLC16A7


Immunogen: Peptide Immunogen


Product Form: Unconjugated

Formulation: Provided as solution in phosphate buffered saline

Concentration: See vial for concentration

For use with Monocarboxylate Transport 2 polyclonal antibodies (Cat. No. X2368P & X2371P).

Functional Analysis: Western Blotting

Positive Control: Testis, spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocyte.

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: Products are stable for one year from purchase when stored properly

Shipping Conditions: Ship at ambient temperature, freeze upon arrival

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

1: Dao L., Landschulz W.H., Landschulz K.T.; Cloning of human monocarboxylate transporter 2 (hMCT2). Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases. 2: Lin R.-Y., Vera J.C., Chaganti R.S.K., Golde D.W.; Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter.; J. Biol. Chem. 273:28959-28965(1998).

Protein Reference(s)

Database Name: UniProt

Accession number: O60669 (Human)

Species Accession: Human

Monocarboxylate Transport 2



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