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Monocarboxylate Transport 2

Catalogue number: X2372B

MCT2; Solute carrier family 16 member 7; SLC16A7

Product Type Blocking Peptide
Units50 µg
Species reactivity Human
Application Western Blot
Product Form

Functions as a proton-linked monocarboxylate transporter and catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a very high affinity pyruvate transporter. MCT2 is a cell membrane; Multi-pass membrane protein with high expression in testis, moderate to low expression in spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocytes. The normal expression of MCT2 is restricted to low levels of expression in normal tissues, but is widely expressed in cancer cells.

Positive Control
Testis, spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocyte.

Peptide Immunogen

See vial for concentration

Provided as solution in phosphate buffered saline

Functional Analysis
Western Blotting

For use with Monocarboxylate Transport 2 polyclonal antibodies (Cat. No. X2368P & X2371P).

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Ship Conditions
Ship at ambient temperature, freeze upon arrival

Product Stability
Products are stable for one year from purchase when stored properly

1: Dao L., Landschulz W.H., Landschulz K.T.; Cloning of human monocarboxylate transporter 2 (hMCT2). Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases. 2: Lin R.-Y., Vera J.C., Chaganti R.S.K., Golde D.W.; Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter.; J. Biol. Chem. 273:28959-28965(1998).

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

Safety Datasheet(s) for this product:

Monocarboxylate Transport 2



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Phone: 978-425-1370