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Monocarboxylate Transport 2

Catalogue number: X2372B

Product Type Blocking Peptide
Units50 µg
HostRabbit
Species reactivity Human
Application Western Blot

Background
Functions as a proton-linked monocarboxylate transporter and catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a very high affinity pyruvate transporter. MCT2 is a cell membrane; Multi-pass membrane protein with high expression in testis, moderate to low expression in spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocytes. The normal expression of MCT2 is restricted to low levels of expression in normal tissues, but is widely expressed in cancer cells.

Synonyms: MCT2; Solute carrier family 16 member 7; SLC16A7

Source

Immunogen: Peptide Immunogen

Product

Product Form: Unconjugated

Formulation: Provided as solution in phosphate buffered saline

Concentration: See vial for concentration

Applications
For use with Monocarboxylate Transport 2 polyclonal antibodies (Cat. No. X2368P & X2371P).

Functional Analysis: Western Blotting

Positive Control: Testis, spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocyte.

Storage
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: Products are stable for one year from purchase when stored properly

Ship Conditions: Ship at ambient temperature, freeze upon arrival

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

References
1: Dao L., Landschulz W.H., Landschulz K.T.; Cloning of human monocarboxylate transporter 2 (hMCT2). Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases. 2: Lin R.-Y., Vera J.C., Chaganti R.S.K., Golde D.W.; Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter.; J. Biol. Chem. 273:28959-28965(1998).

Protein Reference(s)

Database Name: UniProt

Accession number: O60669 (Human)

Species Accession: Human


Monocarboxylate Transport 2

$121.00


Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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