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Monocarboxylate Transport 2


Catalogue number: X2372B

Synonyms
MCT2; Solute carrier family 16 member 7; SLC16A7

Product Type Blocking Peptide
Units50 µg
HostRabbit
Species reactivity Human
Application Western Blot
Product Form
Unconjugated

Background
Functions as a proton-linked monocarboxylate transporter and catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a very high affinity pyruvate transporter. MCT2 is a cell membrane; Multi-pass membrane protein with high expression in testis, moderate to low expression in spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocytes. The normal expression of MCT2 is restricted to low levels of expression in normal tissues, but is widely expressed in cancer cells.

Positive Control
Testis, spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocyte.

Immunogen
Peptide Immunogen

Concentration
See vial for concentration

Formulation
Provided as solution in phosphate buffered saline

Functional Analysis
Western Blotting

Applications
For use with Monocarboxylate Transport 2 polyclonal antibodies (Cat. No. X2368P & X2371P).

Storage
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Ship Conditions
Ship at ambient temperature, freeze upon arrival

Product Stability
Products are stable for one year from purchase when stored properly

References
1: Dao L., Landschulz W.H., Landschulz K.T.; Cloning of human monocarboxylate transporter 2 (hMCT2). Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases. 2: Lin R.-Y., Vera J.C., Chaganti R.S.K., Golde D.W.; Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter.; J. Biol. Chem. 273:28959-28965(1998).

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

Safety Datasheet(s) for this product:

Monocarboxylate Transport 2

$119.00

SKU: X2372B Categories: ,

Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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