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Lysophosphatidic Acid Receptor 1 CT (EDG-2)


Catalogue number: X1269B

Synonyms
Blocking peptide for use in Western blotting with Anti-EDG2 (LPA1) (CT) (Cat. No. C174P)

IsotypeN/A
Product Type Blocking Peptide
Units50 µg
HostN/A
Application Antibody function blocking
Product Form
Unconjugated

Background
Endothelial cell differentiation gene-2 (EDG2), or LPA1, receptor is a high affinity receptor for lysophosphatidic acid (LPA). EDG2 (LPA1), also known as lysophospholipid receptor A1, Vzg-1, mrec1.3 or GPCR26, like all other EDG receptors, couple multiple (3 or more) types of G proteins and transduce decreases in c[AMP]i through Gi and increases in [Ca2+]i by augmenting phospholipase C through Gq/11 and beta/gamma dimers and by induction of PI3 kinase, p125 FAK, phospholipase D by activating rho through G12/13. Human EDG2 (LPA1) is present in high levels on oligodendrocytes and certain human malignant T cell lines. EDG2 (LPA1) receptors (with EDG4) may play a role in protecting cardiomyocytes from apoptosis induced by hypoxia and andrenergic stimulation.

Concentration
See vial for concentration

Formulation
Provided in solution at 1 mg/ml in phosphate buffered saline.

Functional Analysis
Western Blotting

Applications
For use with EDG2 (LPA1) (CT) polyclonal antibody (Cat. No. C174P).

Storage
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Ship Conditions
Ship at ambient temperature, freeze upon arrival

Product Stability
Products are stable for one year from purchase when stored properly

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

Lysophosphatidic Acid Receptor 1 CT (EDG-2)

$119.00

SKU: X1269B Categories: ,