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LNX2

Catalogue number: X2346B

Product Type Blocking Peptide
Units50 µg
HostRabbit
Species reactivity Human
Application Western Blot

Background
Interacts with the phosphotyrosine interaction domain of Numb. Lnx proteins may server as molecular scaffolds that localize unrelated, interacting proteins, such as Numb, to specific subcellular sites. Forms oligomers via their PDZ binding domains to PDZ-binding consensus motifs located in their C-termini or by homophilic oligomerization of their RING fingers.

Synonyms: Numb-binding protein 2, PDZ domain-containing RING finger protein 1

Source

Immunogen: Synthetic peptide derived from human LNX2 protein

Product

Product Form: Unconjugated

Formulation: Provided as solution in phosphate buffered saline

Concentration: See vial for concentration

Applications
For use with LNX2 polyclonal antibodies (Cat. No. X2317P & X2345P).

Functional Analysis: Western Blotting

Positive Control: Protein found in colon and in developing and adult brain.

Storage
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: Products are stable for one year from purchase when stored properly

Ship Conditions: Ship at ambient temperature, freeze upon arrival

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

References
1. Rice, D.S., et al. 'The Lnx family proteins function as molecular scaffolds for Numb family proteins.' Mol Cell Neurosci. 2001 Nov;18(5):525-40. 2. Mirza, M., et al. 'The cell surface protein coxsackie- and adenovirus receptor (CAR) directly associates with the Ligand-of-Numb Protein-X2 (LNX2).' Exp Cell Res. 2005 Sep 10;309(1):110-20.

Protein Reference(s)

Database Name: UniProt

Accession number: Q8N448

Species Accession: Human


LNX2

$121.00


Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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