Catalogue number: X2346B
Numb-binding protein 2, PDZ domain-containing RING finger protein 1
|Product Type||Blocking Peptide|
Interacts with the phosphotyrosine interaction domain of Numb. Lnx proteins may server as molecular scaffolds that localize unrelated, interacting proteins, such as Numb, to specific subcellular sites. Forms oligomers via their PDZ binding domains to PDZ-binding consensus motifs located in their C-termini or by homophilic oligomerization of their RING fingers.
Protein found in colon and in developing and adult brain.
Synthetic peptide derived from human LNX2 protein
See vial for concentration
Provided as solution in phosphate buffered saline
For use with LNX2 polyclonal antibodies (Cat. No. X2317P & X2345P).
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
Ship at ambient temperature, freeze upon arrival
Products are stable for one year from purchase when stored properly
1. Rice, D.S., et al. 'The Lnx family proteins function as molecular scaffolds for Numb family proteins.' Mol Cell Neurosci. 2001 Nov;18(5):525-40. 2. Mirza, M., et al. 'The cell surface protein coxsackie- and adenovirus receptor (CAR) directly associates with the Ligand-of-Numb Protein-X2 (LNX2).' Exp Cell Res. 2005 Sep 10;309(1):110-20.
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Safety Datasheet(s) for this product: