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Lass1 (Cross reacts with GDF1)


Catalogue number: X2294B

Synonyms
LAG1 longevity assurance homolog 1, UOG-1 protein, LAG1, LASS1, LAG1 longevity assurance homolog 1 (LASS 1)

Product Type Blocking Peptide
Units50 µg
Species reactivity Human
Application Western Blot
Product Form
Unconjugated

Background
LAG1 is a longevity gene, the first such gene to be identified. Originally cloned from the yeast Saccharomyces cerevisiae. A close homolog of this gene, LAC1, has been found in the yeast genome. The human homolog of LAG1 has functions in human aging. LAG1 may be involved in neurodegenerative diseases and human aging. Lass1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. Located in the endoplasmic reticulum membrane; LAss1 is a multi-pass membrane protein.

Immunogen
Synthetic peptide derived from the human Lass1 protein.

Concentration
See vial for concentration

Formulation
Provided as solution in phosphate buffered saline with 0.08% sodium azide

Functional Analysis
Antibody Function Blocking

Applications
For use with Lass1 polyclonal antibodies (Cat. No. X2084P & X2310P).

Storage
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Ship Conditions
Ship at ambient temperature, freeze upon arrival

Product Stability
Products are stable for one year from purchase when stored properly

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

Safety Datasheet(s) for this product:

Sodium Azide
/wp-content/uploads/2018/07/Antibody-SDS-with-Sodium-AzideV2.pdf

Lass1 (Cross reacts with GDF1)

$119.00


Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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