Print Friendly, PDF & Email


G-Protein Coupled Receptor 94


Catalogue number: X2375B

Synonyms
P2Y Purinoceptor 13; P2Y13; G-protein coupled receptor 86; GPCR94; GPCR86

Product Type Blocking Peptide
Units50 µg
HostRabbit
Species reactivity Human
Application Western Blot
Product Form
Unconjugated

Background
Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined. Stimulation by ADP in stably transfected CHO cells resulted in inhibition of adenylyl cyclase and the phosphorylation of the MAP kinases MAPK3 and MAPK1 in a pertussis toxin-sensitive way. Inhibition of adenylyl cyclase and phosphorylation of the MAP kinases are transduction mechanisms that involve G(i) proteins.

Immunogen
Synthetic peptide derived from human GPCR94.

Concentration
See vial for concentration

Formulation
Provided as solution in phosphate buffered saline with 0.08% sodium azide

Functional Analysis
Western Blotting

Applications
For use with GPCR94 polyclonal antibodies (Cat. No. X2373P & X2374P).

Storage
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Ship Conditions
Ship at ambient temperature, freeze upon arrival

Product Stability
Products are stable for one year from purchase when stored properly

References
Communi, D, et al. Identification of a novel human ADP receptor coupled to Gi.; J. Biol. Chem. 276:41479-41485(2001).

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

Safety Datasheet(s) for this product:

Sodium Azide
/wp-content/uploads/2018/07/Antibody-SDS-with-Sodium-AzideV2.pdf

G-Protein Coupled Receptor 94

$119.00

SKU: X2375B Categories: ,