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Forkhead box protein P3

Catalogue number: X2349B


Product Type Blocking Peptide
Units50 µg
Species reactivity Human
Application Western Blot
Product Form

Probable transcription factor. Plays a critical role in the control of immune response. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.

Synthetic peptide derived from human FOXP3 protein

See vial for concentration

Provided as solution in phosphate buffered saline

Functional Analysis
Western Blotting

For use with FOXP3 polyclonal antibodies (Cat. No. X2347P & X2348P).

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Ship Conditions
Ship at ambient temperature, freeze upon arrival

Product Stability
Products are stable for one year from purchase when stored properly

1. Bennett, C.L., et al. 'The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3.; Nat. Genet. 27:20-21(2001). 2. Wildin, R.S., et al. 'X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy.; Nat. Genet. 27:18-20(2001). 3. Brunkow, M.E., et al. 'Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.; Nat. Genet. 27:68-73(2001).

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

Safety Datasheet(s) for this product:

Forkhead box protein P3


SKU: X2349B Categories: ,