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Forkhead box protein P3

Catalogue number: X2349B

Product Type Blocking Peptide
Units50 µg
Species reactivity Human
Application Western Blotting

Probable transcription factor. Plays a critical role in the control of immune response. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.

Synonyms: FOXP3


Immunogen: Synthetic peptide derived from human FOXP3 protein


Product Form: Unconjugated

Formulation: Provided as solution in phosphate buffered saline

Concentration: See vial for concentration

For use with FOXP3 polyclonal antibodies (Cat. No. X2347P & X2348P).

Functional Analysis: Western Blotting

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: See expiration date on vial

Shipping Conditions: Ship at ambient temperature, freeze upon arrival

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Exalpha Biologicals accepts no liability for any inaccuracies or omissions in this information.

1. Bennett, C.L., et al. 'The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3.; Nat. Genet. 27:20-21(2001). 2. Wildin, R.S., et al. 'X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy.; Nat. Genet. 27:18-20(2001). 3. Brunkow, M.E., et al. 'Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.; Nat. Genet. 27:68-73(2001).

Protein Reference(s)

Database Name: UniProt

Accession number: Q9BZS1 (Human)

Species Accession: Human

Forkhead box protein P3